Results 121 to 130 of about 929,362 (315)

Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]

open access: yes, 2006
It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

Evaluation of dystrophic calcification in juvenile dermatomyositis and systemic sclerosis

open access: yesActa Pediátrica de México, 2014
Background: Dystrophic calcification is associated with juvenile dermatomyositis and progressive systemic sclerosis. The clinical diagnosis is established with detection of subcutaneous and petrous nodules.
Marimar Saez-de Ocariz
doaj   +1 more source

Targeting Inflammatory T Cells in Multiple Sclerosis: Current Therapies and Future Challenges [PDF]

open access: yes, 2015
Multiple Sclerosis (MS) is an autoimmune inflammatory disorder of the Central Nervous System (CNS), affecting more than one million people worldwide. The pathogenesis of MS involves several genetic and environmental factors, which ultimately lead to ...
Tuosto, Loretta
core   +1 more source

Copeptin as a Biomarker of Microcirculation Alterations in Systemic Sclerosis

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Magdalena Maciejewska,1 Albert Stec,2 Michał Zaremba,2 Cezary Maciejewski,3 Lidia Rudnicka,2 Mariusz Sikora4 1Department of Dermatology, Doctoral School of Medical University of Warsaw, Warsaw, Poland; 2Department of Dermatology, Medical ...
Maciejewska M   +5 more
doaj  

Assessing the Role of Volumetric Brain Information in Multiple Sclerosis Progression [PDF]

open access: yesarXiv
Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions. Deformation-based morphometry utilizes anatomical magnetic resonance imaging to quantitatively assess volumetric brain ...
arxiv  

Angiogenic and angiostatic factors in renal scleroderma-associated vasculopathy [PDF]

open access: yes, 2017
BACKGROUND: The angiogenesis in systemic sclerosis (SSc) is impaired. An imbalance of pro-angiogenic factors and angiogenesis inhibitors has been implicated in the progression of peripheral microvascular damage, defective vascular repair and fibrosis ...
Afeltra, Antonella M. Vittoria   +7 more
core   +1 more source

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