Results 121 to 130 of about 116,133 (341)

Favorable long term effects of intensified immunosuppression combined with therapeutic plasma exchange in patients with early-onset progressive systemic sclerosis-related interstitial lung disease. [PDF]

J Transl Autoimmun, 2022
Potjewijd J, Tobal R, Silvertand D, Gietema HA, Damoiseaux JGMC, van Paassen P.   +5 more
europepmc   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

A case of progressive systemic sclerosis/lupus overlap syndrome: Presenting with parotid swelling. [PDF]

J Oral Maxillofac Pathol, 2021
Ramya R, Swarnalakshmi R, Preethi A, Pradeep R.   +3 more
europepmc   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

The use of the Scleroderma Clinical Trials Consortium Damage Index in systemic sclerosis

Научно-практическая ревматология
Background. The assessment of organ damage in patients with systemic sclerosis (SSc) is challenging. The Scleroderma Clinical Trials Consortium Damage Index (SCTC-DI) proposed in 2019 has not been sufficiently studied and requires testing for wider use ...
L. P. Ananyeva, V. V. Babak, A. D. Koltakova, O. A. Koneva, O. V. Desinova, M. N. Starovoytova, O. B. Ovsyannikova, R. U. Shayakhmetova   +7 more
doaj   +1 more source

POS1326 LONG TERM TREATMENT WITH RITUXIMAB IN PROGRESSIVE SYSTEMIC SCLEROSIS: A MONOCENTRIC RETROSPECTIVE STUDY [PDF]

, 2023
G. Alonzi, G. Natalello, Stefano Fiore, Lucrezia Verardi, E. De Lorenzis, P. G. Cerasuolo, A. Zoli, S. Di Murro, Maria Antonietta D’Agostino, Silvia Laura Bosello   +9 more
openalex   +1 more source

GATA3 Deletion Associated With Juvenile Idiopathic Arthritis: Expanding the Phenotypic Spectrum of Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss, Amanda V. Karam, Julia Shalen, David E. Tunkel, Belina Y. Yi, Kelsey S. Guthrie, Emily M. Kudalkar, Anna E. Patrick, Sonja A. Rasmussen   +8 more
wiley   +1 more source

Successful Treatment of Long-Term Severe Progressive Interstitial Pneumonia with Low-Dose Corticosteroid and Azathioprine in a Patient with Diffuse Systemic Sclerosis

Case Reports in Rheumatology, 2012
For progressive interstitial pneumonia (progressive IP) that accompanies diffuse systemic sclerosis (diffuse SSc), no treatment guidelines have yet been established, and it is a complication with a poor prognosis.
Takuya Kotani, Tohru Takeuchi, Shigeki Makino, Toshiaki Hanafusa   +3 more
doaj   +1 more source

Understanding the Housing and Support Experience of People With Complex Disability in Australia: A Qualitative Analysis of Submissions to the Disability Royal Commission

Australian Journal of Social Issues, EarlyView.
ABSTRACT In 2019, the Australian government established the Royal Commission into Violence, Abuse, Neglect and Exploitation of People with Disability (‘Disability Royal Commission’, DRC) to investigate widespread mistreatment of people with disability. Nearly 10,000 people with disability, their families and supporters engaged with the DRC.
Kate D'Cruz, Fiona Carey, Libby Witts, Jessie Spence, Peter Mulherin, Megan Topping, Di Winkler, Jacinta Douglas   +7 more
wiley   +1 more source

Bridging knowledge gaps: A case report of pulmonary Veno-occlusive disease in systemic sclerosis

Lung India
Pulmonary Veno-Occlusive Disease (PVOD) is a rare cause of pulmonary hypertension (PH) in patients with systemic sclerosis (SSc), posing significant diagnostic and therapeutic challenges.
Shivam Garg, Deepansh Gupta, Girish Sindwani   +2 more
doaj   +1 more source