Results 141 to 150 of about 769,984 (331)

Treatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform

Movement Disorders, EarlyView.
Abstract Background There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...
Cristina Gonzalez‐Robles, Dilan Athauda, Thomas R. Barber, Roger A. Barker, David T. Dexter, Susan Duty, Romy Ellis‐Doyle, Sonia Gandhi, Joel Handley, Edwin Jabbari, Keith Martin, Kevin McFarthing, Georgia Mills, Heather Mortiboys, Stephen Mullin, Rebecca Petty, Esther Sammler, Paula Scurfield, Simon R.W. Stott, George K. Tofaris, Li Wei, Caroline H. Williams‐Gray, Alan Wong, Marie‐Louise Zeissler, Richard K. Wyse, Camille B. Carroll, Thomas Foltynie, Oliver Bandmann, Anthony H.V. Schapira, on behalf of the EJS ACT‐PD Consortium   +29 more
wiley   +1 more source

Serious Neurologic Adverse Events in Tofersen Clinical Trials for Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Tofersen is approved for the treatment of amyotrophic lateral sclerosis (ALS) due to superoxide dismutase 1 mutations (SOD1‐ALS). Here we report serious neurologic adverse events (AEs) that occurred in the tofersen clinical trials in people with SOD1‐ALS.
Alexandra Lovett, Sowmya Chary, Suma Babu, Gaëlle Bruneteau, Jonathan D. Glass, Merete Karlsborg, Shafeeq Ladha, Keith Mayl, Christopher McDermott, Robert C. Bucelli, Adriano Chiò, Toby A. Ferguson, Thos Cochrane, Stephanie Fradette, Karen Smirnakis, Jennifer Inra, Sohail Malek, Laura Fanning   +17 more
wiley   +1 more source

New ELISA Kits using C3 Binding Glycoprotein from Cuscuta europea Detect Mainly IgM CIC in Rheumatoid Arthritis and Progressive Systemic Sclerosis, but not in Systemic Lupus Erythematosus [PDF]

, 2003
С. Станилова, E. Slavov
openalex   +1 more source

Neurofilament Light Chain Levels, Skeletal Muscle Loss, and Nutritional Decline: Key Prognostic Factors in Amyotrophic Lateral Sclerosis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Hypermetabolism and weight loss are established negative prognostic factors in amyotrophic lateral sclerosis (ALS). However, the role of individualized body composition parameters in predicting ALS progression has been underexplored. This study aimed to investigate the correlation between nutritional parameters, neurofilament
Aida Zulueta, Rachele Piras, Domenico Azzolino, Paola Mariani, Riccardo Sideri, Camilla Garrè, Giuliana Federico, Tiziano Lucchi, Paolo Magni, Eugenio Agostino Parati, Christian Lunetta   +10 more
wiley   +1 more source

Progressive Systemic Sclerosis (PSS) and Malignancy, Pulmonary and Non-Pulmonary

, 1979
John H. Talbott, Marcos Barrocas
openalex   +1 more source

Automatic Prediction of Amyotrophic Lateral Sclerosis Progression using Longitudinal Speech Transformer [PDF]

arXiv
Automatic prediction of amyotrophic lateral sclerosis (ALS) disease progression provides a more efficient and objective alternative than manual approaches. We propose ALS longitudinal speech transformer (ALST), a neural network-based automatic predictor of ALS disease progression from longitudinal speech recordings of ALS patients.
arxiv  

Regulation of the terminal complement cascade in adipose tissue for control of its volume, cellularity, and fibrosis

Obesity, EarlyView.
Abstract White adipose tissue (WAT) is a reservoir for various pathogens and their products, such as lipopolysaccharides. Therefore, it must be equipped with a defense mechanism connected with the activation of innate immunity. This explains the phenomenon that adipocytes express components of the classical and alternative complement pathways, which ...
Ilja L. Kruglikov, Philipp E. Scherer
wiley   +1 more source

The role of regional and neuroaxial anesthesia in patients with systemic sclerosis

Local and Regional Anesthesia, 2011
Zoey Sarah Dempsey1, Simone Rowell2, Rose McRobert31Department of Anaesthesia, Southern General Hospital, Glasgow, Lanarkshire, 2Department of Anaesthesia, Western Infirmary, Glasgow, Lanarkshire, 3Department of Anaesthesia, The Ayr Hospital, Ayr ...
Dempsey Z, Rowell S, McRobert R
doaj  

ANA in progressive systemic sclerosis. [PDF]

Annals of the Rheumatic Diseases, 1983
Ugo Picillo, G. Tirri, Mario Giordano, Sergio Migliaresi   +3 more
openaire   +3 more sources

CARDIAC LESIONS IN PROGRESSIVE SYSTEMIC SCLEROSIS

, 1977
Kazuhiko Murata, Keigo Tominaga, Koji Tsunoda, NOBORU BABA, YOSHIMICHI HOJO, Tetsu Shinkai, Toyozo Hashimoto, HIDEAKI SUGA, OSAMU YAMANE, Akira Hasegawa   +9 more
openalex   +2 more sources