LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease [PDF]
Arthritis Care &Research, EarlyView.Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
openalex +2 more sources
Therapeutic options for the treatment of interstitial lung diseases in systemic rheumatic diseases – systemic sclerosis as an example [PDF]
Liječnički vjesnik, 2022 Systemic sclerosis is a multisystem autoimmune disorder characterized by widespread fibrosis, primarily of the skin but also of the lung parenchyma. Interstitial lung disease is one of the most severe manifestations of the disease and a leading cause of ...
Marko Barešić, Branimir Anić
doaj +1 more source
The role of trigger factors in the development of systemic sclerosis (clinical case)
Современная ревматология, 2023 A clinical case of the development of rapidly progressive systemic sclerosis after repeated coronavirus infection is described. The contribution of occupational hazards, the oncological process and radiation therapy to the pathogenesis of this disease is
I. V. Menshikova +3 more
doaj +1 more source
Diagnostics, 2023 Systemic sclerosis (also known as scleroderma) is a chronic fibrosing autoimmune disease with both skin and multisystem organ involvement. Scleroderma has the highest mortality among all rheumatic diseases.
Dariana-Elena Pătrîntașu +7 more
doaj +1 more source
Rheumatology, 2019 Systemic sclerosis is an autoimmune connective tissue disease affecting both skin and internal organs. Progressive disease with multiple organ involvement is considered to have a poor prognosis.
Katarzyna Pawlak-Buś +5 more
doaj +1 more source
Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension [PDF]
, 2014 Pulmonary arterial hypertension is a major complication of systemic sclerosis. Although oxidative stress, intima hyperplasia and a progressive vessel occlusion appear to be clearly involved, the fine molecular mechanisms underpinning the onset and ...
Boin, Francesco +8 more
core +2 more sources
Sero-Negative Systemic Sclerosis: A Rare Presentation [PDF]
Journal of Clinical and Diagnostic Research, 2016 Systemic Sclerosis is a multisystem disease associated with progressive fibrosis of skin and internal organs. It is diagnosed by presence of characteristic clinical findings and is supported by specific serologic abnormalities.
Rakesh Chander +4 more
doaj +1 more source
A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset. [PDF]
, 2012 OBJECTIVE: A prospective observational study of mycophenolate mofetil (MMF) treatment in patients with diffuse progressive cutaneous systemic sclerosis (SSc) of recent onset.
Jimenez, Sergio A. +3 more
core +3 more sources
Audio-vestibular symptoms in systemic autoimmune diseases [PDF]
, 2018 Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce +7 more
core +1 more source
Progressive Systemic Sclerosis and its Dental Implications: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2021 Scleroderma is a complex autoimmune rheumatic disease characterised by the widespread fibrosis of skin and visceral organs, dysregulation of immune system and vasculopathy. The aetiology of this disease remains unknown till now. It is known to exist in
Gor Vani Udaybhai +4 more
doaj +1 more source