Results 11 to 20 of about 929,362 (315)
Severe osteolysis of the mandibular angle and total condylolysis in progressive systemic sclerosis. [PDF]
Case Rep Dent, 2013 Rahpeyma A, Zarch SH, Khajehahmadi S.
europepmc +3 more sources
Frontiers in MedicineObjectivesTo assess in patients with systemic sclerosis (SSc) the concentration of different subpopulations of circulating extracellular vesicles (EVs) and their association with the progression of interstitial lung disease (PF-ILD).MethodsThe ...
J. Colic +8 more
doaj +2 more sources
Therapeutic options for the treatment of interstitial lung diseases in systemic rheumatic diseases – systemic sclerosis as an example [PDF]
Liječnički vjesnik, 2022 Systemic sclerosis is a multisystem autoimmune disorder characterized by widespread fibrosis, primarily of the skin but also of the lung parenchyma. Interstitial lung disease is one of the most severe manifestations of the disease and a leading cause of ...
Marko Barešić, Branimir Anić
doaj +1 more source
State-of-the-art evidence in the treatment of systemic sclerosis
Nature Reviews Rheumatology, 2023 Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease with multi-organ involvement, fibrosis and vasculopathy. Treatment in SSc, including early diffuse cutaneous SSc (dcSSc) and the use of organ-specific therapies, has improved, as ...
J. Pope +5 more
semanticscholar +1 more source
Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension [PDF]
, 2014 Pulmonary arterial hypertension is a major complication of systemic sclerosis. Although oxidative stress, intima hyperplasia and a progressive vessel occlusion appear to be clearly involved, the fine molecular mechanisms underpinning the onset and ...
Boin, Francesco +8 more
core +8 more sources
Skin involvement in early diffuse cutaneous systemic sclerosis: an unmet clinical need
Nature Reviews Rheumatology, 2022 Diffuse cutaneous systemic sclerosis (dcSSc) is associated with high mortality resulting from early internal-organ involvement. Clinicians therefore tend to focus on early diagnosis and treatment of potentially life-threatening cardiorespiratory and ...
A. Herrick, S. Assassi, C. Denton
semanticscholar +1 more source
The role of trigger factors in the development of systemic sclerosis (clinical case)
Современная ревматология, 2023 A clinical case of the development of rapidly progressive systemic sclerosis after repeated coronavirus infection is described. The contribution of occupational hazards, the oncological process and radiation therapy to the pathogenesis of this disease is
I. V. Menshikova +3 more
doaj +1 more source
Progressive systemic sclerosis in the elderly [PDF]
Postgraduate Medical Journal, 1979 Summary There is evidence to suggest that the incidence of progressive systemic sclerosis in the elderly is more common than in younger age groups. As in younger patients, late onset cases may have minimal skin changes and this can cause difficulty in diagnosis. The case histories of 2 patients are presented to illustrate these points.
Dalziel, J, Wilcock, G
openaire +4 more sources
Annals of the Rheumatic Diseases, 2020 Objectives To identify overall disease course, progression patterns and risk factors predictive for progressive interstitial lung disease (ILD) in patients with systemic sclerosis-associated ILD (SSc-ILD), using data from the European Scleroderma Trials ...
A. Hoffmann-Vold +15 more
semanticscholar +1 more source
Journal of Scleroderma and Related Disorders, 2020 The natural history of interstitial lung disease in patients with systemic sclerosis is highly variable. Historical observational studies have demonstrated that the greatest decline in lung function in systemic sclerosis occurs early in the course of the
E. Volkmann
semanticscholar +1 more source