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Progressive systemic sclerosis and the lung
Current Opinion in Pulmonary Medicine, 1998Pulmonary manifestations of systemic sclerosis (scleroderma) are many. The mean survival in these patients is 78 +/- 17 months. Improved diagnostic techniques and better therapeutic options are essential to stem the tide of overwhelming mortality in patients with scleroderma lung disease.
Om P. Sharma, Srihari Veeraraghavan
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Arthritis & Rheumatism, 2011
Systemic sclerosis (SSc; scleroderma) is a connective tissue disorder that is characterized by an obstructive vasculopathy and by the excessive deposition of collagen in the skin and internal organs.
G. Keyszer +7 more
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Systemic sclerosis (SSc; scleroderma) is a connective tissue disorder that is characterized by an obstructive vasculopathy and by the excessive deposition of collagen in the skin and internal organs.
G. Keyszer +7 more
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Progressive Systemic Sclerosis
The Nurse Practitioner, 1982Progressive systemic sclerosis is a disease of uncertain etiology associated with vascular/collagen tissue changes that may affect only the skin (scleroderma) or any and all internal organs (PSS). A disease primarily of Caucasian females, PSS is usually manifested in the fourth to sixth decade of life.
Linda B. Pearson, Linna Walker
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Ketanserin in the Treatment of Progressive Systemic Sclerosis
Angiology, 1988Now progressive systemic sclerosis (PSS) is considered a disease of small vessels with which many immunologic alterations are associated. The presence in the blood of large amounts of serotonin can be considered a very important aggravating factor able to cause the sclerodermic alterations.
G. F. Altomare +2 more
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Epidemiology of Progressive Systemic Sclerosis
Clinics in Rheumatic Diseases, 1979SUMMARY Although PSS may at times be difficult to distinguish from closely related disorders, especially early in its course, a characteristic set of cutaneous and visceral manifestations are helpful in differentiation. The cutaneous sclerosis characteristic of the disease varies in extent from classic diffuse (generalized) scleroderma to the ...
Thomas A. Medsger, Alfonse T. Masi
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Anorectal abnormalities in progressive systemic sclerosis [PDF]
Diseases of the Colon & Rectum, 1989 Seventeen patients with progressive systemic sclerosis (PSS) were evaluated with manometry for anorectal function, and an additional 36 age-matched normal subjects were collected as a control group. The study group had a significant decrement of maximum basal pressure (MBP), 42.6 +/- 27.0 mm Hg, in PSS as compared with the control group, 71.2 +/- 24.9 ...
Jen-Kou Lin +2 more
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Penicillamine and Progressive Systemic Sclerosis
Annals of Internal Medicine, 1983Excerpt To the editor: Steen and associates (1) have attempted to draw conclusions about the effect of D-penicillamine on the natural history of progressive systemic sclerosis with diffuse sclerode...
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Lungs in progressive systemic sclerosis
British Journal of Diseases of the Chest, 1970Summary Impairment of pulmonary function in scleroderma is commoner than would be expected on clinical or radiological grounds alone. There is a poor correlation between the severity of functional derangement and the extent of pulmonary lesion detectable by clinical or radiological means.
J.S. Guleria +3 more
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Some Progress with Systemic Sclerosis
Annals of Internal Medicine, 1979Excerpt The treatment of systemic sclerosis has been ineffectual despite past enthusiasm for some drugs, notably corticosteroids, dimethyl sulfoxide, epsilon aminocaproic acid, potassium para-amino...
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Annals of Internal Medicine, 1967
Excerpt Progressive systemic sclerosis (PSS or scleroderma) occurs in men engaged in many kinds of work, and until recently there has been little reason to suspect that this disease might be prefer...
G. Rodnan +3 more
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Excerpt Progressive systemic sclerosis (PSS or scleroderma) occurs in men engaged in many kinds of work, and until recently there has been little reason to suspect that this disease might be prefer...
G. Rodnan +3 more
semanticscholar +1 more source