Results 251 to 260 of about 116,133 (341)

The Value of Oligoclonal Bands in Multiple Sclerosis Compared to Other Neurological Disorders: A Retrospective Data Analysis From an Austrian Tertiary Center. [PDF]

Eur J Neurol
Monschein T, Scheicher B, Ponleitner M, Krajnc N, Föttinger F, Zrzavy T, Rommer P, Kornek B, Bsteh G, Perkmann T, Berger T, Leutmezer F.   +11 more
europepmc   +1 more source

OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension

Cell Proliferation, EarlyView.
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang, Qing Ni, Yan He, Shijie Liu, Lulu Gan, Anni Dai, Yang Hu, Qian Liu, Xueling Yang, Jiqian Li, Yi Tao, Yunyu Li, Mingyue Xu   +12 more
wiley   +1 more source

Comparative Efficacy of Autologous Hematopoietic and Mesenchymal Stem Cell Transplantation in Patients with Systemic Sclerosis: A Systematic Review. [PDF]

J Clin Med
Bakirova S, Baigenzhin A, Tuganbekova S, Askarov M, Chuvakova E, Doskali M, Doszhan A.   +6 more
europepmc   +1 more source

A case report: The efficacy of pirfenidone in a Chinese patient with progressive systemic sclerosis-associated interstitial lung disease: A CARE-compliant article. [PDF]

Medicine (Baltimore), 2016
Huang H, Feng RE, Li S, Xu K, Bi YL, Xu ZJ.   +5 more
europepmc   +1 more source

Progressive Systemic Sclerosis (CREST Type) with an Intestinal Pseudoobstruction.

, 1998
Junko Tsuji, Tetsuo Sasaki, Takafumi Nishiyama, Satoshi Yamamoto, Hiroshi Nakajima   +4 more
openalex   +1 more source

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

Cell Proliferation, EarlyView.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song, Hyejin Jo, Seokchan Jeong, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Immune cells composition in the skin and subcutaneous adipose tissue of patients with systemic sclerosis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Systemic sclerosis (SSc) is a rare, chronic autoimmune disease characterized by fibrosis of the skin and/or internal organs. Emerging evidence suggests that subcutaneous adipose tissue may contribute to systemic inflammation and fibrosis in SSc.
Marija Geroldinger‐Simić, Ana E. Aguilar González, Gerald Exler, Georg Stary   +3 more
wiley   +1 more source

Appendiceal Perforation From Muscular Thinning in Limited Cutaneous Systemic Sclerosis: A Case Report. [PDF]

Cureus
Nakamura Y, Fujimoto G, Matsuda S, Kusanagi H.   +3 more
europepmc   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Sodium thiosulfate for treatment of nephrogenic systemic fibrosis with metastatic pulmonary calcification in a patient undergoing peritoneal dialysis: a case report. [PDF]

BMC Nephrol
Yan Q, Xu K, Zhu M, Wang D, Liu G, Li D, Zhang J.   +6 more
europepmc   +1 more source