Results 21 to 30 of about 148,737 (346)
Journal of Scleroderma and Related Disorders, 2020 The natural history of interstitial lung disease in patients with systemic sclerosis is highly variable. Historical observational studies have demonstrated that the greatest decline in lung function in systemic sclerosis occurs early in the course of the
E. Volkmann
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Systemic Sclerosis: From Pathophysiology to Novel Therapeutic Approaches
Biomedicines, 2022 Systemic sclerosis (SSc) is a systemic, immune-mediated chronic disorder characterized by small vessel alterations and progressive fibrosis of the skin and internal organs.
D. Benfaremo +4 more
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Rheumatology, 2019 Systemic sclerosis is an autoimmune connective tissue disease affecting both skin and internal organs. Progressive disease with multiple organ involvement is considered to have a poor prognosis.
Katarzyna Pawlak-Buś +5 more
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Sero-Negative Systemic Sclerosis: A Rare Presentation [PDF]
Journal of Clinical and Diagnostic Research, 2016 Systemic Sclerosis is a multisystem disease associated with progressive fibrosis of skin and internal organs. It is diagnosed by presence of characteristic clinical findings and is supported by specific serologic abnormalities.
Rakesh Chander +4 more
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Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosis
Annals of the Rheumatic Diseases, 2021 Objectives Although T cells have been implicated in the pathogenesis of systemic sclerosis (SSc), a comprehensive study of T-cell-mediated immune responses in the affected skin of patients with progressive SSc is lacking.
A. M. Gaydosik +5 more
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Endothelial‐to‐mesenchymal transition in systemic sclerosis
Clinical and Experimental Immunology, 2021 Systemic sclerosis (SSc) is an autoimmune disease characterized by significant vascular alterations and multi‐organ fibrosis. Microvascular alterations are the first event of SSc and injured endothelial cells (ECs) may transdifferentiate towards ...
P. Di Benedetto +7 more
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Progressive Systemic Sclerosis and its Dental Implications: A Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2021 Scleroderma is a complex autoimmune rheumatic disease characterised by the widespread fibrosis of skin and visceral organs, dysregulation of immune system and vasculopathy. The aetiology of this disease remains unknown till now. It is known to exist in
Gor Vani Udaybhai +4 more
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Patients with systemic sclerosis show phenotypic and functional defects in neutrophils
Allergy. European Journal of Allergy and Clinical Immunology, 2021 Systemic sclerosis (SSc) is a multiorgan autoimmune disease characterized by inflammation, vascular modification, and progressive fibrosis of the skin and several visceral organs.
D. Impellizzieri +4 more
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A comparative study of human endogenous retrovirus HERV-E λ 4-1 activation in autoimmune pathology
Медицинская иммунология, 2023 Considering the presence of immunomodulatory properties of human endogenous retroviruses, namely (i) the ability to activate the innate immune response by HERVs nucleic acids; (ii) the antigenicity of transcriptionally competent endogenous retroviruses ...
I. A. Goldina, E. V. Markova
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RADIOLOGICAL FINDINGS IN PROGRESSIVE SYSTEMIC SCLEROSIS (P.S.S.) [PDF]
Acta Medica Iranica, 1980 Radiological findings of 20 patients with scleroderma have been described. We had cornmon and uncommon roentgen signs of scleroderma similar to other series and one case with mid esophagus narrowing which we think have not been reported previously.
M. Eghrari, D. Gol-golab
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