Results 21 to 30 of about 769,984 (331)

Predicting progression of aortic stenosis by measuring serum calcification propensity

Clinical Cardiology, Volume 45, Issue 12, Page 1297-1302, December 2022., 2022
Abstract Background The aim of this prospective, double‐blinded study in patients with aortic sclerosis was to determine whether a new calcification propensity measure in the serum could predict disease progression. Methods We included 129 consecutive patients with aortic sclerosis as assessed during a routine clinical echocardiographic exam. Clinical,
Reto Kurmann, Eric Buffle, Andreas Pasch, Christian Seiler, Stefano F. de Marchi   +4 more
wiley   +1 more source

Double Trouble in Systemic Sclerosis: Complete Heart Block and Systolic Dysfunction [PDF]

Journal of Clinical and Diagnostic Research, 2018
A 26-year-old female, a known case of diffuse systemic sclerosis present with multiple episodes of syncope and progressive dyspnoea over six months.
Akshyaya Pradhan, Sameer Ganpat Vankar, Pravesh Vishwakarma, Rishi Sethi   +3 more
doaj   +1 more source

Systemic sclerosis – diagnostic and therapeutic recommendations of the Polish Dermatological Society. Part 1: diagnosis and monitoring

Przegląd Dermatologiczny, 2017
Systemic sclerosis is an immune-mediated disease characterized by a chronic and progressive course. It often leads to multiorgan failure and patient disability, and contributes to significant reduction in the quality of life.
Dorota Krasowska, Lidia Rudnicka, Aleksandra Dańczak-Pazdrowska, Grażyna Chodorowska, Anna Woźniacka, Anna Lis-Święty, Joanna Czuwara, Joanna Maj, Sławomir Majewski, Anna Sysa-Jędrzejowska, Anna Wojas-Pelc   +10 more
doaj   +1 more source

Frontiers of Targeted Therapy and Predictors of Treatment Response in Systemic Sclerosis

Biomedicines, 2022
Systemic sclerosis (scleroderma, SSc) is one of the most challenging rheumatic diseases, characterized by vasculopathy, dysregulation of the immune response, and progressive tissue fibrosis affecting the skin, lungs, heart, digestive tract, and kidneys [.
Michal Tomcik
doaj   +1 more source

Targeting B cells and plasma cells in autoimmune diseases: From established treatments to novel therapeutic approaches

European Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
B lineage cells have been identified as therapeutic targets in autoimmune diseases. In the current review article, we provide an overview of novel strategies to target B lineage cells in autoimmune diseases, with a focus on inflammatory rheumatic diseases.
Ana Merino‐Vico, Giulia Frazzei, Jan Piet van Hamburg, Sander W. Tas   +3 more
wiley   +1 more source

A companion to the preclinical common data elements and case report forms for in vivo rodent neuroimaging: A report of the TASK3‐WG3 Neuroimaging Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet, Riikka Immonen, Ofer Prager, Alon Friedman, Jens P. Bankstahl, David K. Wright, Terence J. O'Brien, Heidrun Potschka, Olli Gröhn, Neil G. Harris   +9 more
wiley   +1 more source

X-ray Phase Contrast Tomography to assess the sequential evolution of multi-organ damage in an animal model of multiple sclerosis [PDF]

arXiv, 2022
We use X-ray phase-contrast tomography (XPCT) in a multi-organ approach to identify early imaging markers predictive of multiple sclerosis (MS) in EAE animal model. As the majority of neurodegenerative diseases, MS is characterized by a progressive accumulation of biological deficits across different organs and systems.
arxiv  

Benchmarking Continuous Time Models for Predicting Multiple Sclerosis Progression [PDF]

arXiv, 2023
Multiple sclerosis is a disease that affects the brain and spinal cord, it can lead to severe disability and has no known cure. The majority of prior work in machine learning for multiple sclerosis has been centered around using Magnetic Resonance Imaging scans or laboratory tests; these modalities are both expensive to acquire and can be unreliable ...
arxiv  

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Scleroderma-related interstitial lung disease

Respiratory Medicine Case Reports, 2017
Scleroderma-related interstitial lung disease (SSc-ILD) is a pulmonary fibrosing disorder characterized by systemic inflammation and progressive scarring of the lungs that leads to respiratory failure.
Sally Suliman, Abdalhamid Al Harash, William Neil Roberts, Rafael L. Perez, Jesse Roman   +4 more
doaj   +1 more source