The role of allograft inflammatory factor 1 in systemic sclerosis [PDF]
, 2006 Purpose of review: The aim of this article is to review studies which support the hypothesis that allograft inflammatory factor-1, a protein initially identified in chronically rejected cardiac allografts, may be involved in the pathogenesis of the ...
Artlett, Carol M. +2 more
core +3 more sources
Audio-vestibular symptoms in systemic autoimmune diseases [PDF]
, 2018 Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce +7 more
core +1 more source
A comparative study of human endogenous retrovirus HERV-E λ 4-1 activation in autoimmune pathology
Медицинская иммунология, 2023 Considering the presence of immunomodulatory properties of human endogenous retroviruses, namely (i) the ability to activate the innate immune response by HERVs nucleic acids; (ii) the antigenicity of transcriptionally competent endogenous retroviruses ...
I. A. Goldina, E. V. Markova
doaj +1 more source
Boosting multiple sclerosis lesion segmentation through attention mechanism [PDF]
, 2023 Magnetic resonance imaging is a fundamental tool to reach a diagnosis of multiple sclerosis and monitoring its progression. Although several attempts have been made to segment multiple sclerosis lesions using artificial intelligence, fully automated analysis is not yet available.
arxiv +1 more source
Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis. [PDF]
, 2017 BACKGROUND: Gastrointestinal tract (GIT) involvement is a common cause of debilitating symptoms in patients with systemic sclerosis (SSc). There are no disease modifying therapies for this condition and the treatment remains symptomatic, largely owing to
Abraham +105 more
core +2 more sources
Annals of the Rheumatic Diseases, 2019 Objectives To determine whether progressive skin fibrosis is associated with visceral organ progression and mortality during follow-up in patients with diffuse cutaneous systemic sclerosis (dcSSc).
Wanlong Wu +10 more
semanticscholar +1 more source
Patients with systemic sclerosis show phenotypic and functional defects in neutrophils
Allergy. European Journal of Allergy and Clinical Immunology, 2021 Systemic sclerosis (SSc) is a multiorgan autoimmune disease characterized by inflammation, vascular modification, and progressive fibrosis of the skin and several visceral organs.
D. Impellizzieri +4 more
semanticscholar +1 more source
RADIOLOGICAL FINDINGS IN PROGRESSIVE SYSTEMIC SCLEROSIS (P.S.S.) [PDF]
Acta Medica Iranica, 1980 Radiological findings of 20 patients with scleroderma have been described. We had cornmon and uncommon roentgen signs of scleroderma similar to other series and one case with mid esophagus narrowing which we think have not been reported previously.
M. Eghrari, D. Gol-golab
doaj +2 more sources
Assessment of tissue fibrosis in skin biopsies from patients with systemic sclerosis employing confocal laser scanning microscopy: an objective outcome measure for clinical trials? [PDF]
, 2010 OBJECTIVES: To obtain an objective, unbiased assessment of skin fibrosis in patients with SSc for use in clinical trials of SSc disease-modifying therapeutics.
Busquets, Joanna +3 more
core +3 more sources
A Case Report of Systemic Sclerosis Complicated by Biventricular Heart Failure, Pulmonary Hypertension and Review of Literature [PDF]
, 2017 Background: Systemic sclerosis (SSc) is an autoimmune connective tissue disorder whose aetiology is not fully understood. Skin fibrosis and visceral organs involvement are the hallmarks, and the heart could be disproportionately or subtly involved ...
Akinboro AO +3 more
core +1 more source