Assessing clinical utility of Machine Learning and Artificial Intelligence approaches to analyze speech recordings in Multiple Sclerosis: A Pilot Study [PDF]
arXiv, 2021 Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated with speech discrepancies.
arxiv
Synchrotron radiation microtomography of brain hemisphere and spinal cord of a mouse model of multiple sclerosis revealed a correlation between capillary dilation and clinical score [PDF]
J. Comp. Neurol. (2019), 2018 Multiple sclerosis is a neurological disorder in which the myelin sheaths of axons are damaged by the immune response. We report here a three-dimensional structural analysis of brain and spinal cord tissues of a mouse model of multiple sclerosis, known as experimental autoimmune encephalomyelitis (EAE).
arxiv +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Acroosteolysis of distal phalanges in patient with systemic sclerosis – case report
Przegląd Dermatologiczny, 2016 Introduction. Acroosteolysis is a recognized, but under-researched and forgotten manifestation of systemic sclerosis (SSc). Objective . To present a case of exuberant acroosteolysis and subcutaneous tissue calcinosis in the course of SSc.
Zofia Gerlicz-Kowalczuk +4 more
doaj +1 more source
Acta Dermato-Venereologica, 2023 Systemic sclerosis is a progressive connective tissue disease for which there is limited knowledge about physical limitations, quality of life and depression.
Stefanie Heyne +4 more
doaj +1 more source
Prediction of Lung CT Scores of Systemic Sclerosis by Cascaded Regression Neural Networks [PDF]
arXiv, 2021 Visually scoring lung involvement in systemic sclerosis from CT scans plays an important role in monitoring progression, but its labor intensiveness hinders practical application. We proposed, therefore, an automatic scoring framework that consists of two cascaded deep regression neural networks.
arxiv
Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A
Human Mutation, Volume 43, Issue 12, Page 2265-2278, December 2022., 2022 Abstract A rare and fatal disease resembling mucopolysaccharidosis in infants, is caused by impaired intracellular endocytic trafficking due to deficiency of core components of the intracellular membrane‐tethering protein complexes, HOPS, and CORVET. Whole exome sequencing identified a novel VPS33A mutation in a patient suffering from a variant form of
Elena V. Pavlova +11 more
wiley +1 more source
Journal of Medical Science, 2015 Aim. Assessment of infections prevalence rate, type and severity in patients diagnosed with progressive systemic sclerosis (PSS), treated with cyclophosphamide (CTX), during 12 months of observations. Material and methods.
Małgorzata Schlabs +2 more
doaj +1 more source
Treatment of Systemic Sclerosis Associated Interstitial Lung Disease
Journal of Clinical Rheumatology and Immunology, 2020 Systemic sclerosis (SSc) is a systemic connective tissue disorder characterized by progressive skin and visceral organ fibrosis, vasculopathy, and immune dysregulation.
Iris Yan Ki Tang, So Ho
doaj +1 more source
Systemic sclerosis and tachycardia–bradycardia syndrome: a case report
Journal of Medical Case Reports, 2022 Background Systemic sclerosis is a multisystemic character autoimmune disease. It is characterized by vascular dysfunction and progressive fibrosis affecting mainly the skin but also different internal organs.
Raid Faraj +9 more
doaj +1 more source