Results 41 to 50 of about 116,133 (341)

Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]

open access: yes, 2016
Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
core   +1 more source

Acroosteolysis of distal phalanges in patient with systemic sclerosis – case report

open access: yesPrzegląd Dermatologiczny, 2016
Introduction. Acroosteolysis is a recognized, but under-researched and forgotten manifestation of systemic sclerosis (SSc). Objective . To present a case of exuberant acroosteolysis and subcutaneous tissue calcinosis in the course of SSc.
Zofia Gerlicz-Kowalczuk   +4 more
doaj   +1 more source

Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. [PDF]

open access: yes, 2016
OBJECTIVE: To examine whether lung endothelial cells (ECs) from patients with systemic sclerosis (SSc)-associated interstitial lung disease (ILD) express mesenchymal cell-specific proteins and gene transcripts, indicative of the occurrence of endothelial-
Arciniegas   +41 more
core   +2 more sources

Plasma exchange in progressive systemic sclerosis

open access: yesAmerican Journal of Experimental and Clinical Research, 2015
Systemic sclerosis (SSc) is an autoimmune systemic disease of unknown etiology. Present treatment modalities have limited impact on clinical/ laboratory outcomes.
Mohammad Bagher Owlia
doaj   +2 more sources

Coexistence of diabetes mellitus type 1 with diffuse systemic sclerosis – case report and literature review

open access: yesRheumatology, 2017
Diabetic sclerodactyly is a frequently recognized skin finding that may occur in patients with diabetes mellitus but coexistence of diabetes and systemic sclerosis is rare.
Ewa Wielosz   +3 more
doaj   +1 more source

Scleroderma-related interstitial lung disease

open access: yesRespiratory Medicine Case Reports, 2017
Scleroderma-related interstitial lung disease (SSc-ILD) is a pulmonary fibrosing disorder characterized by systemic inflammation and progressive scarring of the lungs that leads to respiratory failure.
Sally Suliman   +4 more
doaj   +1 more source

CXCR4 pos circulating progenitor cells coexpressing monocytic and endothelial markers correlating with fibrotic clinical features are present in the peripheral blood of patients affected by systemic sclerosis [PDF]

open access: yes, 2008
There is still controversy regarding the role of circulating endothelial and progenitor cells (CECs/CEPs) in the pathogenesis of systemic sclerosis (SSc).
CAMPIONI, Diana   +8 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Retrospective analysis of infections prevalence in patients with progressive systemic sclerosis treated with cyclophosphamide

open access: yesJournal of Medical Science, 2015
Aim. Assessment of infections prevalence rate, type and severity in patients diagnosed with progressive systemic sclerosis (PSS), treated with cyclophosphamide (CTX), during 12 months of observations. Material and methods.
Małgorzata Schlabs   +2 more
doaj   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy