Results 51 to 60 of about 769,984 (331)
Advanced Science, EarlyView.The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu +13 more
wiley +1 more source
Fibrinogen Turnover in Progressive Systemic Sclerosis [PDF]
Arthritis & Rheumatism, 1978 AbstractLarge amounts of fibrin are seen in the intima of the renal arterioles in progressive systemic sclerosis (scleroderma). The half‐life or half disappearance time of plasma fibrinogen in 15 patients with scleroderma was studied using 125I fibrinogen to find whether there is an increased turnover of plasma fibrinogen paralleling this morphologic ...
John S. Sergent +6 more
openaire +3 more sources
Learning Myelin Content in Multiple Sclerosis from Multimodal MRI through Adversarial Training [PDF]
, 2018 Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). A reliable measure of the tissue myelin content is therefore essential for the understanding of the physiopathology of MS, tracking progression and assessing treatment efficacy.
arxiv +1 more source
Advanced Science, EarlyView.By studying the maturation mechanisms of vasopressin (AVP), this manuscript identifies FAM134B‐mediated ER‐phagy as a critical pathway for degrading both aggregated proAVP and the key ERAD component, HRD1. HRD1 induction mitigates proAVP aggregation and support AVP neuron function in the absence of autophagy.
Xuya Pan +16 more
wiley +1 more source
Disease progression in systemic sclerosis [PDF]
Rheumatology, 2021 Leeuwen, N.M. van +8 more
openaire +4 more sources
Comparison of Time-to-First-Event and Recurrent Event Methods in Multiple Sclerosis Trials [PDF]
arXiv, 2021 Suppression of disability progression is an important goal in the treatment of multiple sclerosis (MS). Randomized clinical trials in MS frequently use the time to the first confirmed disability progression (CDP) on the ordinal Expanded Disability Status Scale (EDSS) as an endpoint.
arxiv
Advanced Science, EarlyView.In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han +10 more
wiley +1 more source
Progressive System Sclerosis - A Case Report
Journal of Indian Academy of Oral Medicine and Radiology, 2003 Progressive systemic sclerosis is a disease that involves connective tissues and.blood vessels leading to fibrosis. The skin as well as internal organs are involved.
Jyothi S Kumar, L Ashok, G P Mamatha
doaj
Bilateral resorption of mandibular angle in patient with systematic sclerosis - a case report
Journal of Education, Health and Sport, 2022 Progressive systemic sclerosis (PSS) is chronic autoimmune disease affecting a connective tissue. The symptoms of PSS in orofacial area are: restricted mouth opening, xerostomia, facial asymmetry and problems with oral hygiene.
Karolina Futyma-Gąbka +2 more
doaj +1 more source
Multiple Sclerosis Lesion Activity Segmentation with Attention-Guided Two-Path CNNs [PDF]
arXiv, 2020 Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image processing methods can be used to segment lesions and derive quantitative lesion parameters.
arxiv