Results 61 to 70 of about 769,984 (331)

Semaphorin 3E–Plexin D1 Axis Drives Lung Fibrosis through ErbB2‐Mediated Fibroblast Activation

Advanced Science, EarlyView.
TGF‐β1 stimulation in fibroblasts leads to increased Furin expression, Furin‐mediated cleavage of P87‐Sema3E to P61‐Sema3E, which affects fibroblast function through the autocrine pathway, and the P61‐Sema3E‐PlexinD1 axis promotes fibroblast activation, proliferation and migration by affecting ErbB2 phosphorylation, which in turn activates the ErbB2 ...
Zhesong Deng, Jinkun Chen, Ruonan Yang, Yuan Zhan, Shanshan Chen, Jiaheng Zhang, Hao Fu, Yiya Gu, Qian Huang, Jixing Wu, Lianyu Shan, Abdelilah Soussi Gounni, Jungang Xie   +12 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Plasma exchange in progressive systemic sclerosis

American Journal of Experimental and Clinical Research, 2015
Systemic sclerosis (SSc) is an autoimmune systemic disease of unknown etiology. Present treatment modalities have limited impact on clinical/ laboratory outcomes.
Mohammad Bagher Owlia
doaj  

Uncommon skeletal findings in systemic sclerosis (scleroderma)

South African Journal of Radiology, 2002
Scleroderma or progressive systemic sclerosis is a diffuse disease characterised by excessive deposition of collagen and small-vessel arteritis. Systemic sclerosis is divided into two groups. 1.
Betsie van der Walt, Irma van de Werke, Zarina Lockhat   +2 more
doaj   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Disability prediction in multiple sclerosis using performance outcome measures and demographic data [PDF]

arXiv, 2022
Literature on machine learning for multiple sclerosis has primarily focused on the use of neuroimaging data such as magnetic resonance imaging and clinical laboratory tests for disease identification. However, studies have shown that these modalities are not consistent with disease activity such as symptoms or disease progression. Furthermore, the cost
arxiv  

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

Aggregate, EarlyView.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang, Alice Le Friec, Menglin Chen, Di Sun   +3 more
wiley   +1 more source

Successful conservative management of pathological mandibular fracture resulting from chronic osteomyelitis in a 90‐year‐old woman

Oral Science International, Volume 20, Issue 1, Page 42-47, January 2023., 2023
Abstract Background We report the successful conservative management of a pathological mandibular fracture resulting from chronic osteomyelitis in a super‐elderly patient. Case Presentation A 90‐year‐old woman was admitted because of an external dental fistula with purulent drainage. Radiographs showed extensive bone destruction in the mandible.
Ryutaro Ono, Takeshi Amemiya, Toshiro Yamamoto, Narisato Kanamura   +3 more
wiley   +1 more source

Bronchioloalveolar Carcinoma in Progressive Systemic Sclerosis

The Korean Journal of Internal Medicine, 1987
Bronchioloalveolar carcinoma(BAC) is the most common histological type of lung cancer arising in an area of scar tissue, and it is frequently superimposed in the fibrotic lung of progressive systemic sclerosis(PSS). The so called scar cancer is believed to be caused by the transformation of hyperplastic epithelium to metaplasia and finally to neoplasia
Do Yung Shin, Myoung Suk Park, Tae Sun Jin, Youn Bok Jang, Duk Jae Shun   +4 more
openaire   +3 more sources

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, EarlyView.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source