PPAR? Downregulation by TGF in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis [PDF]
, 2010 The nuclear orphan receptor peroxisome proliferator-activated receptor-gamma (PPAR-γ) is expressed in multiple cell types in addition to adipocytes. Upon its activation by natural ligands such as fatty acids and eicosanoids, or by synthetic agonists such
A Galli +75 more
core +19 more sources
Learning Myelin Content in Multiple Sclerosis from Multimodal MRI through Adversarial Training [PDF]
, 2018 Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). A reliable measure of the tissue myelin content is therefore essential for the understanding of the physiopathology of MS, tracking progression and assessing treatment efficacy.
arxiv +1 more source
Comparison of Time-to-First-Event and Recurrent Event Methods in Multiple Sclerosis Trials [PDF]
arXiv, 2021 Suppression of disability progression is an important goal in the treatment of multiple sclerosis (MS). Randomized clinical trials in MS frequently use the time to the first confirmed disability progression (CDP) on the ordinal Expanded Disability Status Scale (EDSS) as an endpoint.
arxiv
Disease progression in systemic sclerosis [PDF]
Rheumatology, 2021 Leeuwen, N.M. van +8 more
openaire +4 more sources
Progressive System Sclerosis - A Case Report
Journal of Indian Academy of Oral Medicine and Radiology, 2003 Progressive systemic sclerosis is a disease that involves connective tissues and.blood vessels leading to fibrosis. The skin as well as internal organs are involved.
Jyothi S Kumar, L Ashok, G P Mamatha
doaj
Multiple Sclerosis Lesion Activity Segmentation with Attention-Guided Two-Path CNNs [PDF]
arXiv, 2020 Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image processing methods can be used to segment lesions and derive quantitative lesion parameters.
arxiv
Evaluation of estimated glomerular filtration rate and clinical variables in systemic sclerosis patients [PDF]
, 2016 Objectives: The most important renal complication of systemic sclerosis (SSc) is scleroderma renal crisis (SRC). Many patients demonstrate less severe renal complications, most likely associated with reduced renal blood flow and a consequent reduction in
Amoroso, Antonio +7 more
core +1 more source
Uncommon skeletal findings in systemic sclerosis (scleroderma)
South African Journal of Radiology, 2002 Scleroderma or progressive systemic sclerosis is a diffuse disease characterised by excessive deposition of collagen and small-vessel arteritis. Systemic sclerosis is divided into two groups. 1.
Betsie van der Walt +2 more
doaj +1 more source
Bilateral resorption of mandibular angle in patient with systematic sclerosis - a case report
Journal of Education, Health and Sport, 2022 Progressive systemic sclerosis (PSS) is chronic autoimmune disease affecting a connective tissue. The symptoms of PSS in orofacial area are: restricted mouth opening, xerostomia, facial asymmetry and problems with oral hygiene.
Karolina Futyma-Gąbka +2 more
doaj +1 more source
Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]
, 2010 The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V. +2 more
core +2 more sources