Results 251 to 260 of about 21,193 (336)

Patient‐derived surgical samples reveal the cellular and molecular signatures of glioblastoma infiltration in distinct radiological zones

Brain Pathology, EarlyView.
Integrated histological and transcriptional profiling of the glioblastoma periphery reveals clinically relevant tumor infiltration beyond MRI‐defined boundaries. MRI‐guided biopsies from contrast‐enhancing (CE), non‐contrast‐enhancing (nCE), edema (E), and radiologically normal (N) regions demonstrate that nCE areas frequently retain neoplastic and ...
Olaya de Dios, Juan Romero, María de los Ángeles Ramírez‐González, Beatriz Herranz, Alicia Avis‐Bodas, Juliana Manosalva, Diego Megías, Ana Ramos, Juan Manuel Sepúlveda‐Sánchez, Ricardo Gargini, Berta Segura‐Collar, Gabriel Velilla, Bárbara Meléndez, Pedro González, Luis Jiménez‐Roldán, Guillermo García‐Posadas, Aurelio Hernández‐Laín, Ángel Pérez‐Núñez, Pilar Sánchez‐Gómez   +18 more
wiley   +1 more source

Doxorubicin paclitaxel in pretreated advanced small-cell lung cancer: a large real-life retrospective study. [PDF]

Transl Lung Cancer Res
Cheuvart C, Gougis P, Campedel L, Bourrachot C, Rolland Debord C, Abbar B.   +5 more
europepmc   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

The multivariate shared truncated normal frailty model with application to medical data. [PDF]

Sci Rep
Gallardo DI, Gómez YM, Santibañez JL, Venegas O, Bourguignon M.   +4 more
europepmc   +1 more source

Entrepreneurial State as a Creative Destroyer: Comparison of Hong Kong and Singapore's Creative Industries

Creativity and Innovation Management, EarlyView.
ABSTRACT This paper explores the limits of mission‐directed entrepreneurial states by drawing on the theory of recombinant innovation and F.A. Hayek's insights on the spontaneous growth of knowledge in society. First, the use of discretionary policymaking curtails the range of knowledge generated in the process of social interaction, limiting the scope
Bryan Cheang, Praharsh Mehrotra
wiley   +1 more source

Gemcitabine-docetaxel therapy in pediatric patients with relapsed or refractory sarcoma: a single-center experience. [PDF]

Front Pediatr
Çil M, Yağcı BG.
europepmc   +1 more source

Genetic Predictors of Progression and Skin Rash in Japanese mCSPC Patients Treated With Apalutamide: CUARTET Study

Cancer Science, EarlyView.
In patients with mCSPC treated with apalutamide plus ADT, baseline ctDNA predicted earlier progression to CRPC and worse overall survival. Exploratory genome‐wide analysis identified 12 SNPs associated with apalutamide‐related skin rash. ABSTRACT Despite promising evidence of the efficacy of the androgen deprivation therapy (ADT) plus apalutamide in ...
Masaki Shiota, Taku Naiki, Koji Hatano, Akira Yokomizo, Hiroaki Tsuchiya, Yoko Takahashi, Taku Nakayama, Masaki Yoshida, Hirotsugu Uemura   +8 more
wiley   +1 more source

On multicomponent stress-strength reliability for progressively censored logistic exponential model.

Alex Eng J
Mahto AK, Abhishek K, Tripathi YM, Balogun OS, Tashkandy YA, Bakr ME.   +5 more
europepmc   +1 more source

Performance of Circulating Inflammatory Biomarkers and Krebs von den Lungen 6 for Predicting Progressive Pulmonary Fibrosis in Patients With Systemic Sclerosis-Associated Interstitial Lung Disease. [PDF]

ACR Open Rheumatol
Yomono K, Huang S, Khanna D, Kuwana M.
europepmc   +1 more source

Schools as Sites of Activism: Students' Political Socialisation and Activism at School

Children &Society, EarlyView.
ABSTRACT This paper explores students' political socialisation and activism at school. It draws on research from two datasets: interviews with 24 activists aged 15–25, and data from a national survey of 1600 school students in Wales. Wales offers a unique perspective as a case study for the enactment of young people's civil and political rights, given ...
Rhian Barrance, Esther Muddiman, Mark Connolly, Kate Marston   +3 more
wiley   +1 more source