Results 91 to 100 of about 22,412 (293)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The long run effects of changes in tax progressivity [PDF]
This paper compares the steady state outcomes of revenue-neutral changes to the progressivity of the tax schedule. Our economy features heterogeneous households who differ in their preferences and permanent labor productivities, but it does not have ...
Daniel R. Carroll, Eric R. Young
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Lecturas de Economía, 2013 One of the main functions of health care systems is to collect enough revenue to finance health expenditures. This revenue can be obtained through different sources (taxes, social insurance contributions, out-of-pocket payments, donations), each of which
Aurelio Mejía Mejía
doaj
Jurnal Kedokteran Hewan, 2018 The aim of this study was to know the effect of red dragon fruit (Hylocereus polyrhizus) peel ethanol extract at dose of 0.25, 0.5, and 1 mg/g bw on endometriosis progressivity, signed by granuloma, on mouse model of endometriosis.
Anindya Hapsari, Yanuar Eka Pujiastutik
doaj +1 more source
Are Progressive Income Taxes Stabilizing? : A Reply [PDF]
Dromel and Pintus [Are Progressive Income Taxes Stabilizing?, Journal of Public Economic Theory 10, (2008) 329-349] have shown that labor-income tax progressivity reduces the likelihood of local indeterminacy, sunspots and cycles in a one sector monetary
Chen, Yan, Zhang, Yan
core +1 more source
Tax and Spending Policy and Economic Mobility [PDF]
, 2008 Surveys the literature on how economic mobility is affected by federal tax policies such as the Earned Income Tax Credit and deductions for home ownership; government spending on education and health care; and income supports such as Social ...
Brenda Cushing-Daniels +1 more
core
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Avoiding initiation of repair in L2 conversations-for-learning [PDF]
, 2017 Using audio-recorded data from second language (L2) English conversations-for-learning between an L2 user of English and a first language (L1) user of English (the researcher), this study analyzes cases in which the L1 user avoids initiation of repair ...
Eric Hauser
core +2 more sources
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source