Results 131 to 140 of about 1,065,082 (380)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Influence of proinflammatory cytokine gene polymorphism on childhood obesity

European Journal of Medical Research, 2009
Background Obesity development is a complex process which can be influenced by genetic predisposition modified by environmental factors. Nowadays, the problem of overweight and obesity, including related complications, occurs in increasingly younger ...
Popko K, Górska E, Pyrzak B, Telmaszczyk-Emmel A, Wisniewska A, Majcher A, Wasik M, Demkow U   +7 more
doaj   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Clinical Features of the Course of Chronic Epstein-barr Viral Infection Depending on the Type of Immune Reaction of Organism [PDF]

, 2016
The results of the study of the main regulatory cytokines levels in patients with chronic forms of EBV-infection (CEBV) are presented the work.Aim of research.
Liadova, T. (Tatiana)
core  

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Both STAT3 activation and cholesterol efflux contribute to the anti-inflammatory effect of apoA-I/ABCA1 interaction in macrophages

Journal of Lipid Research, 2016
ABCA1 exports excess cholesterol from cells to apoA-I and is essential for HDL synthesis. Genetic studies have shown that ABCA1 protects against cardiovascular disease.
Chongren Tang, Barbara A. Houston, Carl Storey, Renee C. LeBoeuf   +3 more
doaj   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Age-related differences in the cytokine profile in the lungs of Syrian hamsters (Mesocricetus auratus) infected with SARS-CoV-2 virus [PDF]

BIO Web of Conferences
Cytokine profile and age play a significant role in COVID-19. A hyperinflammatory response caused by proinflammatory cytokines can lead to cytokine storm and tissue damage. And the levels of interferons, which play an essential role in antiviral immunity,
Fomin Gleb, Islamov Rinat
doaj   +1 more source

Recombinant Human Interleukin‐10 Fails to Alter Proinflammatory Cytokine Production or Physiologic Changes Associated with the Jarisch‐Herxheimer Reaction [PDF]

, 2000
Philip J. Cooper, Daniel Fekade, Daniel G. Remick, Paul Grint, Janice C. Wherry, George E. Griffin   +5 more
openalex   +1 more source

Celiac Disease Pathogenesis: The Proinflammatory Cytokine Network

Journal of Pediatric Gastroenterology and Nutrition, 2008
ABSTRACTIn susceptible individuals, the adaptive response, mediated by the activation of antigen‐specific T lymphocytes, drives a proinflammatory response, which ends in an immune‐mediated enteropathy characterized by villous atrophy, crypt hyperplasia, and recruitment of intraepithelial lymphocytes. In addition, some gluten peptides are able to induce
José Antonio, Garrote, Emma, Gómez-González, David, Bernardo, Eduardo, Arranz, Fernando, Chirdo   +4 more
openaire   +3 more sources