Results 181 to 190 of about 1,021,035 (396)

Curcumin Blocks Cytokine-Mediated NF-κB Activation and Proinflammatory Gene Expression by Inhibiting Inhibitory Factor I-κB Kinase Activity [PDF]

, 1999
Christian Jobin, Cynthia A. Bradham, Maria Pia Russo, Booker Juma, Acharan S. Narula, David A. Brenner, R. Balfour Sartor   +6 more
openalex   +1 more source

Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ

Proceedings of the National Academy of Sciences of the United States of America, 2017
Joseph S. Ainscough, T. Macleod, D. McGonagle, Rosella Brakefield, J. Baron, A. Alase, M. Wittmann, M. Stacey   +7 more
semanticscholar   +1 more source

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

Advanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang, Su Hyun Jung, Seyong Kwon, Sung Jin Park, Joo H. Kang   +4 more
wiley   +1 more source

An IkappaB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophages

, 1996
Penny P. Powell, Linda K. Dixon, R. M. E. Parkhouse   +2 more
openalex   +1 more source

Downregulation of proinflammatory cytokine release in whole blood from septic patients [PDF]

, 1995
Wolfgang Ertel, JP Kremer, J. Kenney, Ursula Steckholzer, Doraid Jarrar, O. Trentz, F. W. Schildberg   +6 more
openalex   +1 more source

Identifying Myeloid‐Derived Suppressor Cells and Lipocalin‐2 as Therapeutic Targets for Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Inflammatory dysregulation drives intervertebral disc degeneration via stage‐dependent immune cellular dynamics. Single‐cell transcriptomics and genetic risk mapping revealed a shift from LCN2high myeloid‐derived suppressor cells maintaining disc repair in early stages to IL1B+ macrophage‐dominated pathology in advanced disease.
Changmeng Zhang, Haoyun Li, Hongfei Wang, Liangyu Shi, Ying Shing Chan, Yu Wang, Graham Ka Hon Shea   +6 more
wiley   +1 more source

Dynamics of proinflammatory cytokine expression in the joints of mice with collagen-induced arthritis (CIA) [PDF]

, 1997
L Marinova-Mutafchieva, Richard Williams, Lesley Mason, Claudia Mauri, Marc Feldmann, Ravinder N. Maini   +5 more
openalex   +1 more source

Inhibition of Phosphodiesterase 10A by MP‐10 Rescues Behavioral Deficits and Normalizes Microglial Morphology and Synaptic Pruning in A Mouse Model of FOXP1 Syndrome

Advanced Science, EarlyView.
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich, Jing Wang, Ferdinand Althammer, Tim Schubert, Nina Kluck, Valery Grinevich, Stefanie Schmitteckert, Christian P. Schaaf, Gudrun A. Rappold   +8 more
wiley   +1 more source

Both STAT3 activation and cholesterol efflux contribute to the anti-inflammatory effect of apoA-I/ABCA1 interaction in macrophages

Journal of Lipid Research, 2016
ABCA1 exports excess cholesterol from cells to apoA-I and is essential for HDL synthesis. Genetic studies have shown that ABCA1 protects against cardiovascular disease.
Chongren Tang, Barbara A. Houston, Carl Storey, Renee C. LeBoeuf   +3 more
doaj  

Proinflammatory Cytokine and Nitric Oxide Induction in Murine Macrophages by Cell Wall and Cytoplasmic Extracts of Lactic Acid Bacteria

, 1999
Maria V. Tejada‐Simon, James J. Pestka
openalex   +1 more source