Results 221 to 230 of about 1,021,035 (396)

Severe acute malnutrition promotes bacterial binding over proinflammatory cytokine secretion by circulating innate immune cells. [PDF]

Sci Adv, 2023
Phiri TN, Mutasa K, Rukobo S, Govha M, Mushayanembwa P, Mwakamui S, Haider T, Zyambo K, Dumbura C, Tome J, Runodamoto T, Chidamba L, Majo FD, Ngosa D, Chandwe K, Kapoma C, Mwapenya B, Mufukari W, Sturgeon JP, Robertson RC, Smuk M, Ntozini R, Nathoo K, Amadi B, Kelly P, Bwakura-Dangarembizi M, Prendergast AJ, Bourke CD.   +27 more
europepmc   +1 more source

Novel Quaternary Ammonium Salt‐Linked STING Agonist Antibody‐Drug Conjugate: Synergistic Activation of Tumor Immunity with Mitigated Off‐Target Toxicity

Advanced Science, EarlyView.
Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long, Borui Tang, Fei Xie, Lianqi Liu, Yangyihua Zhou, Jingwen Dong, Jianfeng Wang, Cuicui Sun, Yuting Wang, Ruoqi Li, Na Zhang, Liping Li, Longlong Luo, Junhai Xiao, Wu Zhong, Dian Xiao, Hongbin Deng, Xinbo Zhou   +17 more
wiley   +1 more source

Therapeutic Ultrasound Modulates Cell Proliferation and Proinflammatory Cytokine Levels in Osteoarthritic Chondrocytes. [PDF]

J Cell Mol Med
Yilmaz AÇ, Toktas H, Celik S, Sen S.
europepmc   +1 more source

Inhibitory Activity of Natural cis-Khellactone on Soluble Epoxide Hydrolase and Proinflammatory Cytokine Production in Lipopolysaccharides-Stimulated RAW264.7 Cells. [PDF]

Plants (Basel), 2023
Kim JH, Park JH, Koo SC, Huh YC, Hur M, Park WT, Moon YH, Kim TI, Cho BO.   +8 more
europepmc   +1 more source

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

Proinflammatory cytokine-induced alpha cell impairment in human islet microtissues is partially restored by dual incretin receptor agonism. [PDF]

Diabetologia
Henriksen K, Rufer C, Title AC, Jawurek S, Hartmann B, Holst JJ, Knop FK, Yesildag B, Størling J.   +8 more
europepmc   +1 more source

Pregabalin inhibits proinflammatory cytokine release in patients with fibromyalgia syndrome. [PDF]

Arch Rheumatol, 2023
Ellergezen P, Alp A, Çavun S, Çelebi M, Macunluoğlu AC.   +4 more
europepmc   +1 more source

Decreased Cytomegalovirus Expression Following Proinflammatory Cytokine Treatment of Primary Human Astrocytes [PDF]

, 2000
Maxim C.‐J. Cheeran, Shuxian Hu, Genya Gekker, James R. Lokensgard   +3 more
openalex   +1 more source

AuCu@CuO2 Aerogels with H2O2/O2 Self‐Supplying and Quadruple Enzyme‐Like Activity for MRSA‐Infected Diabetic Wound Management

Advanced Science, EarlyView.
The AuCu@CuO2 aerogels demonstrate favorable photothermal properties, four types of enzyme‐like activities, and H2O2/O2 self‐supplying to modulate the complex microenvironment of MRSA‐infected diabetic wounds. The results indicate that the AuCu@CuO2 aerogel can be activated by the microenvironment of diabetic wound infection, alleviating inflammation ...
Xiaofeng Tan, Nanyun Lin, Sha Yang, Hongyu Gong, Minghui Wang, Na Li, Fen Liu, Dajun Rao, Yingying Wu, Jing Tang, Qinglai Yang   +10 more
wiley   +1 more source

Hepatokine and Proinflammatory Cytokine Profile in Patients with Carotid Atherosclerosis and Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

Biomedicines
Cano-Contreras AD, Francisco MDR, Vargas-Basurto JL, González-Gómez KD, Vivanco-Cid H, Hernández-Flores KG, Grube-Pagola P, Roesch-Dietlen FB, Remes-Troche JM.   +8 more
europepmc   +1 more source