Deoxynivalenol modulated mucin expression and proinflammatory cytokine production, affecting susceptibility to enteroinvasive Escherichia coli infection in intestinal epithelial cells. [PDF]
Wan MLY+4 more
europepmc +1 more source
Copper Super-Dosing Improves Performance of Heat-Stressed Broiler Chickens through Modulation of Expression of Proinflammatory Cytokine Genes. [PDF]
Haldar S+4 more
europepmc +1 more source
γδ-T Cells Are Critical for Survival and Early Proinflammatory Cytokine Gene Expression During MurineKlebsiellaPneumonia [PDF]
Thomas A. Moore+3 more
openalex +1 more source
USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang+9 more
wiley +1 more source
Streptolysin S induces proinflammatory cytokine expression in calcium ion-influx-dependent manner. [PDF]
Yamamori Y+5 more
europepmc +1 more source
Chronic stress and age-related increases in the proinflammatory cytokine IL-6
J. Kiecolt-Glaser+5 more
semanticscholar +1 more source
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv+8 more
wiley +1 more source
Genome Sequencing and Assembly of Enterotoxigenic Escherichia coli E9034A: Role of LngA, CstH, and FliC in Intestinal Cell Colonization and the Release of the Proinflammatory Cytokine IL-8. [PDF]
Rodríguez-Martínez R+10 more
europepmc +1 more source