Results 81 to 90 of about 16,534,485 (359)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Развитие образованияThe requirements of federal state educational standards, professional standards and the labor market contribute to the introduction of project-based learning into the educational process of the university.
Olga Y. Glukhova +2 more
doaj +1 more source
BOOK REVIEW OF NOTHING LASTS FOREVER WRITTEN BY SIDNEY SHELDON [PDF]
, 2015 A novel entitled Nothing Lasts Forever was written by Sidney Sheldon. The novel is about the life and strugle of three woman doctors who work in Embarcadero County Hospital, San Fransisco.
Verdiana, Mutia
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Logiques de projet et régulation publique de l’information géographique
Netcom, 2013 Based on the experience of the spatial data infrastructure project carried out by the Bolivian Government (GeoBolivia), this article aims at studying the geo-environmental information data heritage owned by the country after two decades of « by project »
Louca Lerch
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Les pratiques d’orientation en direction des personnes malades chroniques
Perspectives Interdisciplinaires sur le Travail et la Santé, 2017 This article presents individual and collective career guidance practices towards people suffering from chronic disease, who are looking for coming back to work. It takes part of an action-research about what can help or restrain this coming-back.
Joëlle Mezza
doaj +1 more source