Results 61 to 70 of about 14,002,155 (301)

From organising as projects to projects as organisations

International Journal of Project Management, 2008
Nowadays, projects and project management can be found in virtually all organisations. Accordingly, preventing project failure has become increasingly critical. In light of this, attempts have been made to redefine the conceptual bases of project management and to define new avenues for research, development of the field, and practical application.
Molloy, E, van Donk, D
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Nouveaux espaces publics

Communiquer, 2015
In order to find new ways of thinking about communication, it is important to analyse ruptures and transformations of spaces for exchanges and for dialogues.
Bernard Lamizet
doaj   +1 more source

The Life Project [PDF]

Electronic Workshops in Computing, 2012
The Life Project explores issues of psychological projection into technology by diving into the convoluted relationship between practical purpose and emotional attachment, through both the creative act of designing and making robot entities with artificial emotions, and the social act of engaging with them.
Baker, C, French, F, Raskob, E, Rothwell, N   +3 more
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The Boltzmann project [PDF]

Metrologia, 2018
Abstract The International Committee for Weights and Measures (CIPM), at its meeting in October 2017, followed the recommendation of the Consultative Committee for Units (CCU) on the redefinition of the kilogram, ampere, kelvin and mole. For the redefinition of the kelvin, the Boltzmann constant will be fixed with
J. Fischer, B. Fellmuth, C. Gaiser, T. Zandt, L. Pitre, F. Sparasci, M. D. Plimmer, M. de Podesta, R. Underwood, G. Sutton, G. Machin, R. M. Gavioso, D. Madonna Ripa, P. P. M. Steur, J. Qu, X. J. Feng, J. Zhang, M. R. Moldover, S. P. Benz, D. R. White, L. Gianfrani, A. Castrillo, L. Moretti, B. Darquié, E. Moufarej, C. Daussy, S. Briaudeau, O. Kozlova, L. Risegari, J. J. Segovia, M. C. Martín, D. del Campo   +31 more
openaire   +6 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

DEVELOPMENT OF THE STATE SUPPORT FORMS PROJECTS IN INDUSTRIAL BUILDING

Вестник Дагестанского государственного технического университета: Технические науки, 2016
Aim. The topicality of the research is stipulated by the objective necessity of the organizational and economic mechanism improvement of the state support projects of the industrial building.
I. M. Meilanov, A. M. Esetova
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The MAJORANA Project

Journal of Physics: Conference Series, 2009
Building a \BBz experiment with the ability to probe neutrino mass in the inverted hierarchy region requires the combination of a large detector mass sensitive to \BBz, on the order of 1-tonne, and unprecedented background levels, on the order of or less than 1 count per year in the \BBz signal region. The MAJORANA Collaboration proposes a design based
Varner, R.L., Schubert, A.G., Bertrand, F.E., Shirchenko, M., Farmer, T., Johnson, R.A., Myers, A.W., Yin, Z.-B., Hossbach, T., Finnerty, P., Ejiri, H., Akashi-Ronquest, M., Howe, M.A., Marino, M.G., Efremenko, Yu., Boswell, M., Vetter, K., Doe, P.J., Guiseppe, V.E., Wouters, J.M., Miley, H.S., Fast, J., Nomachi, M., Elliott, S.R., Hoppe, E., Chan, Y.-D., Amsbaugh, J.F., Greenberg, C., Dunmore, J.A., Kidd, M., Burritt, T.H., Tornow, W., Barbeau, P., Wilkerson, J.F., Timkin, V., Kephart, J., Hallin, L., Amman, M., Orrell, J., Shima, T., Fujikawa, B., Hurley, D., Bugg, W., Egorov, V., Keller, C., Odom, B., MacMullin, S., Gusey, K., Cianciolo, T.V., Hazama, R., Creswick, R., Luke, P., Barabash, A.S., Aalseth, C.E., Vanyushin, I., Yakushev, E., Leviner, L., Detwiler, J.A., Collar, J., Kouzes, R.T., Yu, C.-H., Kochetov, O., Rykaczewski, K.P., Tull, C., Robertson, R.G.H., Keillor, M., Back, H.O., Farach, H., McDonald, A.B., Young, A.R., Ely, J., Bergevin, M., Hime, A., Warner, R., Rodriguez, L., Thompson, R., Poon, A.W.P., Baktash, C., Cromaz, M., Konovalov, S.I., Radford, D.C., Van Wechel, T.D., Hyronimus, B., Mei, D.-M., Riley, N., Esterline, J., Rielage, K., Henning, R., Avignone, F.T., III, Beene, J.R., Gehman, V.M., Brudanin, V., Prior, G., Reeves, J.H., Yumatov, V., Lesko, K.T.   +95 more
openaire   +2 more sources