Results 51 to 60 of about 9,090,705 (261)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The amoebic growth of project costs
, 2005 In the public arena, we often hear about projects that have suffered massive cost overruns. Often they are related to large public construction projects such as airports, bridges, or public buildings.
Ackermann, F. +6 more
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Proceedings of the IEEE, 2014 The spiking neural network architecture (SpiNNaker) project aims to deliver a massively parallel million-core computer whose interconnect architecture is inspired by the connectivity characteristics of the mammalian brain, and which is suited to the modeling of large-scale spiking neural networks in biological real time.
Steve B. Furber +3 more
openaire +1 more source
Women's March on Washington Archives Project
, 2017 Women's March on Washington Archives Project seeks to collect oral histories and photographs capturing the Women's March on Washington, January 21st ...
Women's March on Washington Archives Project
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Projects and Project Temporalities
Social Anthropology/Anthropologie SocialeAbstract The project form – a goal-driven approach to resource allocation and task coordination – is one of the most widespread organisational technologies in the world today. Significantly, projects are pervasive organisers of time. They tether activity to schedules. They entail social synchronisations and disruptions.
Andrew Graan, Carl Rommel
openaire +3 more sources
Project manager competency development framework
, 2017 Building on the framework developed in the previous edition, Project Manager Competency Development Framework - Third Edition extends the framework both vertically (to include program and portfolio managers) and horizontally (to cover continued ...
Project Management Institute
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source