Results 41 to 50 of about 9,090,705 (261)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Project Whirlwind summary report no. 50, second quarter 1957 [PDF]
Includes: review and problem index, current problems arranged according to field of application, current problems arranged according to the mathematics involved; Whirlwind coding and applications, introduction and progress reports; academic, introduction,
Project Whirlwind Research Staff
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The-SmartH2O-project/models: Models of SmartH2O project
Models of SmartH2O project <p>This repository contains the SmartH2O agent-based models for the district of <strong>Valencia</strong>, Spain (top folder <code>emivasa</code>) and the district of <strong>Terre di ...
The SmartH2O project
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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Arkansas Autumn Project collection
This collection contains material generated by the Arkansas Autumn ...
Arkansas Autumn Project
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Describes how to apply PERT with MS Project software. PERT provides a mechanism to explicitly include uncertainty in task durations in a project plan. It is relatively easy to implement. Describes its limitations.
Pons, D.
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