Results 121 to 130 of about 354,602 (309)
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
A policy analysis of aid coordination and management in the health sector of Bangladesh : assessing the instruments, exposing the agendas, and considering the prospects for government leadership. [PDF]
In the 1990s, the coordination and management of aid in the health sector became more firmly established on policy agendas as a result of concern that the increased volume of aid and increasing number and diversity of donors in the sector was leading ...
Buse, Dieter Kent
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
One Step at a Time: Does Gradualism Build Coordination? [PDF]
We study how gradualism -- increasing required levels (“thresholds”) of contributions slowly over time rather than requiring a high level of contribution immediately -- affects individuals’ decisions to contribute to a public project.
Plamen Nikolov +2 more
core
, 2020 Through an extensive literature review, this study develops a comprehensive operational model, rooted in social network theory, to investigate the influence of knowledge sharing on perceived project performance, relational coordination, and meeting ...
Anichenko, Ekaterina
core
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Rolul managerului de proiect în implementarea proiectelor cu finanțare europeană
Revista Transilvană de Ştiinţe Administrative, 2014 The present article is intended to develop an analysis of the role that the project manager has in project implementation from a dual perspective: his/her involvement in implementing EU-fnanced projects, and coordination, as a means to orient and ...
Natalia Monica BALOGH, Martin BALOGH
doaj
Frontiers in Earth ScienceThe Baltic Sea Region (BSR) is a major arena for circular water innovation, supported by EU investment exceeding €20.5 million in recent years. Yet moving from technically successful pilots to wider regional implementation remains difficult.
Cheryl Marie Cordeiro, Erik Sindhøj
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source