Results 121 to 130 of about 10,618,865 (261)

Processes Underpinning Successful Co‐Design: Lessons From a Digital Health Project

Health Expectations
Background Co‐design helps to align research with end‐user needs, but there is no consistent method for reporting co‐design methodology and evaluation. We share our experiences co‐designing the Love Your Brain digital platform for stroke prevention.
Catherine Burns, Monique F. Kilkenny, Tara Purvis, Seana L. Gall, Christine Farmer, Seamus Barker, Brenda Booth, Janet E. Bray, Dominique A. Cadilhac, Jan Cameron, Lachlan L. Dalli, Stephanie Ho, Eleanor Horton, Timothy Kleinig, Lisa Murphy, Mark R. Nelson, Muideen T. Olaiya, Amanda G. Thrift, Rosanne Freak‐Poli   +18 more
doaj   +1 more source

Little ears – Aboriginal programmes for hearing and EAR screening (LEAP – HEAR): a research protocol for co-design workshops to strengthen programmes

BMJ Open
Introduction Multiple well-considered but siloed initiatives and programmes exist in Australia to support ear and hearing screening and assessment for Indigenous children.
Catherine M McMahon, Kai Nash, Luke Halvorsen, Katrina Ward, Kiri Mealings, David MacQueen   +5 more
doaj   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

Evaluation of Electronic Palliative Care Coordination Systems to support advance care planning for people living with life-threatening conditions (PREPARE): protocol for a multicentre observational study using routinely collected primary and secondary care data in England

BMJ Open
Introduction Electronic Palliative Care Coordination Systems (EPaCCS) are electronic registers that aim to facilitate documentation and sharing of up-to-date information about patients’ end-of-life preferences and plans for care among different health ...
Christina Ramsenthaler, Katherine E Sleeman, Jonathan Koffman, Joanne Droney, Peter May, Matthew J Allsop, Diane Laverty, Rashmi Kumar, Céire E Costelloe, Julia Verne, Kavitha Saravanakumar, John Rosling, Alastair Bearne, Margaret Powell, Marcel Alied, Sophie Law-Clucas, Lisa Scerri, Rebekah Williams, Denzil James   +18 more
doaj   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Policy Coordination Committee Charter of the Consortium Board [PDF]

, 2014
Policy Coordination Committee Charter of the Consortium ...
CGIAR Consortium Board
core   +1 more source

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Advanced Healthcare Materials, EarlyView.
Systematic investigation of antibody orientation strategies in lateral flow immunoassays reveals that a para‐substituted (aminomethyl)phenylboronic acid mediated probe (P‐6) combined with a biotin‐streptavidin test‐line modification achieves a synergistic 14‐ to 19‐fold sensitivity gain over conventional conjugation. Furthermore, multiplexed detection,
Pin‐Hao Wang, Shunmuga Nathan Shunmuga Nainar, Bing‐Han Zhuang, Shun‐Mao Yang, Hong‐Cheu Lin, Yang‐Hsiang Chan   +5 more
wiley   +1 more source

An AI-Enabled Predictive Harm Response Management Algorithmic Tool to Reduce Adverse Events in Health Care Settings (PreHaRM): Protocol for a Three-Phase Model Development and Pilot-Testing Study

JMIR Research Protocols
BackgroundCurrent data analysis and coordination methods do not effectively support nurses and midwives in risk reduction, as retrospective reporting does not allow real-time insights and precludes proactive, preventive care ...
Marion Eckert, Greg Sharplin, Wolfgang Mayer, Georg Grossmann, Jan Stanek, Gourav Gupta, Lachlan Darch, Markus Stumptner, Nicholas Marlow   +8 more
doaj   +1 more source

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

Advanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar, Daan Vorselen, Jai Prakash   +2 more
wiley   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source