Results 181 to 190 of about 9,735,717 (300)

The State of Corporate Governance Research [PDF]

This paper, which introduces the special issue on corporate governance co-sponsored by the Review of Financial Studies and the National Bureau of Economic Research (NBER), reviews and comments on the state of corporate governance research.
Michael S. Weisbach, Lucian A. Bebchuk
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

From principles to practice: an actionable framework for AI governance in healthcare organisations. [PDF]

BMJ Digit Health Ai
Freeman S, Wang A, Saraf S, Potts E, Mckimm A, Coiera E, Magrabi F.   +6 more
europepmc   +1 more source

Project Management : Governing Projects in NGOs

Abstract Non-Governmental Organizations (NGOs) operate in environments characterized by structural complexity, donor-driven accountability requirements, and heterogeneous operational capacities. Unlike commercial enterprises, NGOs do not merely execute projects; they are fundamentally structured by them.
openaire   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Negotiating cultural voice in the platform era: the access-representation nexus in Asia-Pacific screen production. [PDF]

Front Sociol
Anphanlam A.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Evolutionary dynamics of a four-stakeholder ecosystem for misinformation governance on short-video platforms. [PDF]

R Soc Open Sci
Song X, Song W.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Determinants of collaboration dynamics and challenges in North-South data-driven health research in the African context: an epistemic injustice perspective. [PDF]

Front Res Metr Anal
Bekele R, Moen A, Belina M, Saranto K, Berhane K.   +4 more
europepmc   +1 more source