Results 141 to 150 of about 46,567 (296)
Measuring governance and service delivery in safety net programs [PDF]
This paper develops a framework to assess organizational performance in the delivery of social safety nets. Specifically, it provides guidance to task teams and program managers for identifying indicators of governance and service quality in targeted ...
Rubio, Gloria M.
core
RiverRiver ethics, a significant advancement inspired by Chinese President XI Jinping's ecological civilization thought, embodies the philosophical essence of river governance and represents a legacy of innovation by generations of water resources ...
Yunchang Zhang +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
The political economy of the clean development mechanism (CDM) governance system.
In spite of the exponentially increasing volume of the CDM system of the Kyoto Protocol, very few have so far come up with scholarly political economy analysis of its governance system.
Nedergaard, Peter
core
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
The Effectiveness of Governance Mechanisms in Crowdfunding
, 2019 During the last years, crowdfunding gained attention as alternative source of funding for a variety of projects. More and more creative, artistic and entrepreneurial projects search funding through the crowd.
Blohm, Ivo, Schulz, Moritz
core
GOVERNANCE MECHANISMS AND INFRASTRUCTURE PROJECT SUCCESS: THE ROLE OF GRIEVANCE REDRESS SYSTEMS
International Journal of Advanced ResearchInfrastructure development remains central to economic transformation, particularly in developing countries where investments in transport, energy, water, and telecommunications underpin growth and service delivery (Ika & Pinto, 2022; Turner & Zolin, 2024).
openaire +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source