Results 41 to 50 of about 5,104,399 (355)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Digital Core Modeling Based on Pretrained Generative Adversarial Neural Networks
Geofluids, 2022 Accurately establishing a 3D digital core model is of great significance in oil and gas production. The physical experiment method and numerical modeling method are common modeling methods.
Qing Zhang +5 more
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Seismic Response Analysis of Jointed Rock Slope under Pulse-Like Ground Motions
Advances in Civil EngineeringBecause of the forward directivity effects, energy concentration, and fling step effect of pulse-like ground motions, it is easy to cause landslide of jointed rock slope.
Xijun Jia, Yu Zhang, Ziyi Zhang
doaj +1 more source
Ekonomika Poljoprivrede (1979)The presented study analyzes the impact of green initiatives and new technologies on the tourist experience and user satisfaction in rural areas of western Serbia, focusing on the differences between younger and older populations. Through regression and
Asmaeil Ali Mohammed Khmaaj +4 more
doaj +1 more source
Stakeholder management strategies during construction project work [PDF]
, 2016 This paper engages with stakeholder management practices from the building phase of hospital construction projects to analyse the methods employed by contractor and client in a construction project context. A series of vignettes illustrating stakeholder
Andersen ES +7 more
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Working up to work: Perceived employability of students commencing a project management degree
Project Leadership and Society, 2022 The successful acquisition of employment is influenced by a number of parameters, including the individual's perception that they are employable.
Guinevere Gilbert +2 more
doaj +1 more source
Analyzing Project Management Maturity Level in Indonesia [PDF]
, 2013 Project management has been generally known and increasingly used by many organizations to gain competitive advantage. In this context, many studies have proposed maturity models to evaluate how project management knowledge has been deployed effectively ...
Silva, E. N. (Elisabeth) +1 more
core +3 more sources