Results 51 to 60 of about 1,795,714 (315)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
The Indian Journal of Agricultural Sciences, 2014 A field experiment was conducted during 2007-08 and 2010-11 at Belvatagi, Karnataka to study the effect of irrigation and crop residue mulching on water use efficiency and yield of maize (Zea mays L.) - chickpea (Cicer arietinum L.) sequence under no ...
S RAJKUMARA +3 more
doaj +1 more source
Digital Core Modeling Based on Pretrained Generative Adversarial Neural Networks
Geofluids, 2022 Accurately establishing a 3D digital core model is of great significance in oil and gas production. The physical experiment method and numerical modeling method are common modeling methods.
Qing Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Construction Economics and Building, 2016 This paper aims to review the use of various construction procurement systems and present the development of Relationship-Based Procurement (RBP) Methods currently in use within the Australian construction industry.
Farshid Rahmani +2 more
doaj +1 more source
Motivation in Project Management: The Project Manager's Perspective [PDF]
Project Management Journal, 2008 Project motivation is a key aspect to a successful project, yet few studies exist that shed light on this important subject. This article reviews the current literature and theoretical aspects of motivation and provides an analysis of the data. A survey was conducted by soliciting project managers to tell how they perceive their ability to influence ...
Bernhard Schmid, Jonathan Adams
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The standard for organizational project management (OPM)
, 2018 The Standard for Organizational Project Management (OPM) provides a framework and integrated approach using portfolio, program, and project management to deliver organizational strategy for better performance, better results, and a sustainable ...
Project Management Institute
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