Results 41 to 50 of about 5,479,050 (257)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Project risk management for community-based post-disaster housing reconstruction project [PDF]

open access: yes, 2013
Indonesia is a highly disaster prone country, particularly to earthquakes. In the last decade, Indonesia has been hit by three large earthquakes; Aceh in December 2004, Yogyakarta in May 2006, and West Sumatra in September 2009.
Amaratunga, Dilanthi   +2 more
core  

Library project management in a collaborative web-based working environment [PDF]

open access: yes, 2003
This paper discusses the emerging paradigm of project management performed in a web-based working environment. It highlights how project management and its associated features are strongly linked to fulfilling quality and value criteria for customers ...
Barry Dickson   +4 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Analisis Penerapan Project Management Information System (PMIS) Menggunakan Metode Technology Acceptance Model (TAM) Studi Kasus PT. INDOSAT, Tbk [PDF]

open access: yes, 2014
Project Management Information System (PMIS) adalah suatu sistem alat dan teknik yang digunakan dalam manajemen proyek untuk menyampaikan informasi.
Rizal, A. (Arizal)
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Town of Newington Stormwater Management Project [PDF]

open access: yes, 2010
The UNH Stormwater Center worked with the Newington Planning Board to improve the town’s site plan review regulations to better manage ...
Town of Newington
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Social Media Marketing Integration: Agile Project Management [PDF]

open access: yes, 2017
The implementation of digital and social media strategies to currently existing marketing strategies requires extensive knowledge and expertise. Project management techniques and practices can be utilized to implement this change and determine its ...
Holst, Ida M
core   +1 more source

Exploration and project management [PDF]

open access: yesInternational Journal of Project Management, 2008
Project management in academic studies tends to be regarded as an adequate solution to the problems raised by innovation. This paper sets out to question this tendency to equate projects and innovation which, in our view, can lead to the improper use of projects to manage innovation.
openaire   +3 more sources

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