Results 141 to 150 of about 17,302,014 (354)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

USING THE DELPHI TECHNIQUE AND EFQM MODEL APPROACH TO BUILD A CONCEPTUAL MODEL FOR CONSTRUCTION PROJECT PERFORMANCE

Фінансово-кредитна діяльність: проблеми теорії та практики
This study presents a new conceptual framework for evaluating the performance of construction projects, based on an adaptation of the European Foundation for Quality Management (EFQM) model.
Ван Люй Тонг, Труонг Ван Луу   +1 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Impact of strategic and servant leadership on project performance: measurement model for improvement in project performance

, 2023
El modelado con ecuaciones estructurales ha aportado grandes ventajas en el entendimiento del desempeño en proyectos, aunque de igual manera ha incrementado la complejidad con que los mismos son analizados, por tanto, esta investigación tiene como ...
Steve Pulido, Jason, Roa Rodríguez, Guillermo, Muñoz Peña, Fernando Andrés   +2 more
core   +1 more source

Ambidextrous Leadership and Sustainability-Based Project Performance: The Role of Project Culture

, 2017
Most studies in the project management field emphasized the effects of leaders or managers, but these effects have rarely been examined at the project level.
Junwei Zheng, Guangdong Wu, Hongtao Xie, H. Xu   +3 more
semanticscholar   +1 more source

Good countries or good projects ? macro and micro correlates of World Bank project performance [PDF]

The authors use data from more than 6,000 World Bank projects evaluated between 1983 and 2009 to investigate macro and micro correlates of project outcomes.
Denizer, Cevdet, Kraay, Aart, Kaufmann, Daniel   +2 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Absorptive, innovative and adaptive capabilities and their impact on project and project portfolio performance

, 2012
This study explores how absorptive, innovative and adaptive capabilities within early project phases affect project and portfolio performances in pharmaceutical and biotechnology R&D organizations.
Müller, Ralf,, Biedenbach, Thomas,
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The Pinoke Project Performance

, 2015
The Pinoke Project is a 6 week creative development to create a full-length transmedia dance performance at the cutting edge of artificially intelligent technology, elite contemporary dance practice, and publication.
J McCormick (13278936), S Hutchinson (9890732), J Kaye (7632203), P Divers (13668895), JB Vincent (14797912)   +4 more
core