Results 161 to 170 of about 17,302,014 (354)

The impact of project capabilities on project performance: Case of open source software projects

, 2012
Open Source Software (OSS) projects are contingent on volunteer developers and voluntary contributions from users, accordingly, traditional performance measures used for software projects, like being on time and budget, and satisfying specifications, may
Aurum, Aybuke, Ghapanchi, Amir Hossein, Amir Hossein Ghapanchi, Aybuke Aurum   +3 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

CLIENT PROJECT TIME SCHEDULE CONTROLS — AN EMPIRICALLY-BASED SYSTEM DYNAMICS CONCEPTUAL MODEL

South African Journal of Industrial Engineering, 2018
Different project participants often have different objectives and expectations, and implement different controls aimed at advancing their interests.
Alfred Mutizwa Chitongo, Leon Pretorius
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A Fuzzy Approach on Earned Value Method to Evaluate Project Performance in Solojebres Commuter Depot

Rekayasa Sipil
The high level of public interest in using the Solo-Jogja commuter needs to be accompanied by an effort to improve the services and reliability of facilities, one of which is the establishment of a Commuter Depot located at Solojebres Station.
Ahmad Kahfi Firdausi, M. Ruslin Anwar, Arief Rachmansyah   +2 more
doaj   +1 more source

Integrating a Collaborative Management Model into a Project Scorecard for efficient Cross-Company Project Management [PDF]

, 2008
Proceedings of the 2008 AIPM Project Management Conference 12-15 October, 2008, National Convention Centre, Canberra, ACT ...
Plischke, D, Niebecker, KD, Eager, DM, Kubitza, K   +3 more
core  

What\u27s Left of Rights? Arendt and political ontology in the anthropocene

, 2019
My project in this paper is to make a perverse, post-human, and even queer return to Arendt’s thinking on the ontological foundation of rights, to ask: What is left of rights?
Werry, Margaret
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The Impact of Organizational Readiness on Financial and Project Performance from the Employee's Perspective

Jurnal Teknik Industri
The COVID-19 pandemic forced non-essential sectors to limit operations, leading to financial decline. Organizational readiness to adopt digital technology has become critical for firms' survival.
Zahwa Fitria Gumilang, Budhi Prihartono
doaj   +1 more source