Results 51 to 60 of about 12,470,638 (289)

Reforming Project Management: The Role of Planning, Execution and Controlling [PDF]

open access: yes
In this paper, we focus on the need for reforming the role of plans, execution (or action) and control in project management. We argue that the present style of project management, as described in the Guide to the Project Management Body of Knowledge ...
Koskela, Lauri, Howell, Greg
core   +3 more sources

Natural capital accounting reveals ecosystems’ role in water and energy security in Colombia’s Sinú Basin

open access: yesCommunications Earth & Environment
Many valuable economic benefits from nature have traditionally been overlooked in both national accounts and government policy. To remedy this, countries are adopting the new United Nations System of Environmental-Economic Accounting framework for ...
Lisa Mandle   +7 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Real project planning : developing a project delivery strategy /

open access: yes, 2008
Get yourself equipped with more than just methodologies and lean how to be a trusted project leader.Includes bibliographical references and index.Print version record.Front cover; Real project planning; Copyright page; About the author; About the Project
Melton, Trish.
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

A hierarchical approach to multi-project planning under uncertainty. [PDF]

open access: yes
We survey several viewpoints on the management of the planning complexity of multi-project organisations under uncertainty. A positioning framework is proposed to distinguish between different types of project-driven organisations, which is meant to aid ...
Wullink, G   +3 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Hospital Planning Office Guidelines: Health Board Project Teams

open access: yes, 1977
This paper descrIbes the work of, a project team In the briefIng design, construction and commissioning of hospital building projects under classification 3.1 (d) Hospital Planning Office Guidelines (Hospital Planning Office 2)
Department of Health (DoH)   +1 more
core  

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