Results 131 to 140 of about 237,675 (304)
Timeslack-based techniques for generating robust projectschedules subject to resource uncertainty. [PDF]
The classical, deterministic resource-constrained project scheduling problem has been the subject of a great deal of research during the previous decades. This is not surprising given the high practical relevance of this scheduling problem. Nevertheless,
Lambrechts, Olivier +2 more
core
Advanced Science, EarlyView.Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang +12 more
wiley +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Quilts (The Names Project Quilt), 1988
, 1988 Schedule of events and other details relating to the NAMES Project Quilt display in Washington, D ...
NAMES Project
core
Advanced Science, EarlyView.A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang +19 more
wiley +1 more source
Summary report no. 7, April 1948 [PDF]
, 2009 Includes: foreword, Project Whirlwind, the Whirlwind computers, and reports; general status; summary schedule; arrangement of Whirlwind I apparatus; storage, deflection circuits, and tests of 5-inch storage tube; dynamic analysis of D-C load; conversion ...
Project Whirlwind Research Staff
core
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Advanced Science, EarlyView.AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li +6 more
wiley +1 more source
Heuristic procedures for reactive project scheduling. [PDF]
This paper describes new heuristic reactive project scheduling procedures that may be used to repair resource-constrained roject baseline schedules that suer from multiple activity duration disruptions during project execution.The objective is to ...
Van de Vonder, S +3 more
core
Summary report no. 12, September 1948 [PDF]
, 2009 Includes: foreword, Project Whirlwind, the Whirlwind computers, and reports; general status; indoctrination program for new staff members; visitors, summary schedule; storage tube Beryllium mosaics formed by evaporation, formation of the mosaic, use of ...
Project Whirlwind Research Staff
core