Results 91 to 100 of about 1,391,169 (305)
Наука КрасноярьяThere are two main methods commonly used for decision-making: multi-criteria analysis (MCA) and cost-benefit analysis (CBA). The significance of this research lies in the fact that currently, the rationale behind the final decision in choosing among ...
Oleg N. Makarov +2 more
doaj +1 more source
A project contingency framework based on uncertainty and its consequences
, 2010 There is an increasing diversity both of project types and PM approaches, but decision tools and theory connecting the two are limited. To address this shortcoming, this paper reviews literature on alternative PM approaches, in the context of project ...
Windahl, Charlotta +5 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Mini project : automated selection machine : document transcript
, 2010 This is Mini Project documentation about automated selection machines. It is part of the 2009/10 BEng in Electrical Engineering (course number 2ELE0066) from the University of Hertfordshire.
University of Hertfordshire, School of Electronic Communications and Electrical Engineering
core
Ethical objections to sex selection for nonmedical reasons [PDF]
, 2008 This paper examines the main ethical argument used to support the use of sex selection for non-medical reasons, namely that sex selection for non-medical reasons should be allowed on the grounds of reproductive autonomy.
Frith, Lucy; id_orcid +3 more
core +1 more source
A decision support process for the selection of sustainable public ICT project investments
International Journal of Information Systems and Project ManagementThe allocation of limited public resources to public investments necessitates selecting projects with the highest social and economic value, along with the greatest likelihood of success.
Muhammed Rasit Ozdas +3 more
doaj +1 more source
Six Sigma Project Selection Using Extent Fuzzy AHP: An Empirical Study [PDF]
International Journal of Research in Industrial Engineering, 2013 Six sigma is a project driven approach that concentrates on reducing variations, defects and improving the quality of products, processes as well as services.
S.K. Tiwari, R.K. Singh, S.C. Srivastava
doaj
Project external environmental factors affecting project delivery systems selection
Journal of Civil Engineering and Management, 2019 Project delivery systems (PDSs) selection is crucial to construction project management success. The matching between construction projects and PDSs is hypersensitive to project external environment.
Bingsheng Liu +4 more
doaj +1 more source