Results 71 to 80 of about 1,391,169 (305)
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A scenario based project portfolio selection [PDF]
One of the primary assumptions in many project portfolio selection is the availability of all parameters. However, in real-world cases, many parameters are under uncertainty and the exact values are unknown in advance.
Kamran Pourahmadi +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Project Portfolio Selection with the Maximization of Net Present Value [PDF]
Projects scheduling by the project portfolio selection, something that has its own complexity and its flexibility, can create different composition of the project portfolio.
Mostafa Nikkhah Nasab, Amir Abbas Najafi
doaj
Evolutionary projection selection for Radon barcodes [PDF]
To appear in proceedings of The 2016 IEEE Congress on Evolutionary Computation (IEEE CEC 2016), July 24-29, 2016, Vancouver ...
Hamid R. Tizhoosh, Shahryar Rahnamayan
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A state-of-art survey on project selection using MCDM techniques [PDF]
Project selection is considered as the first essential part of project portfolio management. Project selection is also considered as a process to evaluate each project idea and chooses the one with the biggest priority.
Soheil Sadi-Nezhad
doaj +1 more source
A benchmark study on the effectiveness of search-based data selection and feature selection for cross project defect prediction [PDF]
Context: Previous studies have shown that steered training data or dataset selection can lead to better performance for cross project defect prediction(CPDP). On the other hand, feature selection and data quality are issues to consider in CPDP.Objective:
Seyedrebvar Hosseini +5 more
core +1 more source
Belgacom: IT Project Selection 2005
This teaching case features a situation at Belgacom, the leading telecommunications company in Belgium, end of April 2005. Wim Bouckenooghe, newly appointed finance director of Belgacom’s Network and IT division within the Fixed Line Services (FLS) segment, is troubled by the effectiveness of the selection of the discretionary IT projects, particularly
Stijn Viaene +2 more
openaire +2 more sources

