Results 41 to 50 of about 1,363,756 (217)

Developing a project portfolio selection model for contractor firms considering the risk factor

open access: yesJournal of Civil Engineering and Management, 2012
Regarding to the high importance of project selection in the project life cycle, solving bid/no-bid problems, especially in the construction industry, is a subject of most recent research.
Hamidreza Abbasianjahromi   +1 more
doaj   +1 more source

Multi objective project portfolio selection [PDF]

open access: yesJournal of Project Management, 2019
The Project Portfolio Selection is a complex process that involves many factors and considerations since the project is proposed until the project portfolio is finally selected.
Kamal Baqeri   +2 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Local action groups and the LEADER co-financing of rural development projects in Slovenia

open access: yesAgricultural Economics (AGRICECON), 2014
The influence of a formal and informal system of the Local Action Group (LAG) board's performance on the perception of its members is analysed in association with the suitability of the rural development projects for the LEADER funds co-financing.
Alenka VOLK, Štefan BOJNEC
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Methodologies for Technology Selection in an Industry 4.0 Environment: A Methodological Analysis Using ProKnow-C

open access: yesTechnologies
In an ever-evolving digital environment, organizations must adopt advanced technologies for real-time big data processing to maintain their competitiveness and growth. However, selecting appropriate technologies is a challenge, particularly for small and
Luis Quezada   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A scenario based project portfolio selection [PDF]

open access: yesManagement Science Letters, 2015
One of the primary assumptions in many project portfolio selection is the availability of all parameters. However, in real-world cases, many parameters are under uncertainty and the exact values are unknown in advance.
Kamran Pourahmadi   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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