Results 41 to 50 of about 3,423,376 (310)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Century Farms Carry on Tradition [PDF]

open access: yes, 2006
A collaborative research project explores the success of century ...
Davis, Laura
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Re-imagining the Iron Triangle: Embedding Sustainability into Project Constraints [PDF]

open access: yes, 2013
Since the emergence of the formal discipline of project management, academics and practitioners have sought to define criteria against which project success can be measured.
Ebbesen, Jonas Balshoej, Hope, Alex
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Identification and evaluation of the critical success factors for construction projects in Lithuania: AHP approach

open access: yesJournal of Civil Engineering and Management, 2014
This paper proposes the Analytic Hierarchy Process (AHP) as a tool to rank different critical success factors (CSFs) for construction projects in Lithuania. Considering the current lack of understanding of CSFs within the local context, this study is one
Neringa Gudienė   +3 more
doaj   +1 more source

Project Successful Deployment

open access: yesInternational Journal of Online and Biomedical Engineering (iJOE), 2022
In this paper, we present a method for evaluating the success of digitalization projects, namely the Project Successful Deployment (PSD). With the term digitalization, we mean the use of digital technologies and digitized information to create value in new ways and to benefit from them.
Giovanni Romagnoli   +2 more
openaire   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Ladder to Success – Eliciting Project Managers’ Perceptions of IS Project Success Criteria

open access: yesInternational Journal of Information Systems and Project Management, 2014
The traditional approach to assess information system (IS) project success is adherence to planning (ATP) – meeting budget, schedule, and requirements targets. Today, scholars agree that ATP is insufficient to adequately assess IS project success, but an
Oleg Pankratz, Dirk Basten, , ,
doaj   +1 more source

Exploratory study regarding how cultural perspectives can influence the perceptions of project success in Brazilian companies

open access: yesProduction, 2016
Due to globalization and dynamic business environment, teams in companies are multicultural; as a result, culture may become an important aspect to be considered.
Pamela Adelino Ramos   +1 more
doaj   +1 more source

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