Results 61 to 70 of about 3,423,376 (310)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

The Impact of Project Management Methodologies on Project Success: A Case Study of the Oil and Gas Industry [PDF]

open access: yesJournal of Engineering, Project, and Production Management, 2019
Oil and gas industry is complex and competitive and its projects are characterized by their importance and complexity. To achieve sustainability, oil and gas firms have to initiate and complete projects to scope, schedule, cost and quality.
Hazem Abdulla, Mukhtar Al-Hashimi
doaj   +1 more source

Increasing Student Success at Minority-Serving Institutions: Findings From the BEAMS Project [PDF]

open access: yes, 2008
Details the five-step process used at over one hundred campuses to craft data-driven action plans to improve student success as part of the BEAMS (Building Engagement and Attainment for Minority Students) initiative.
Lacey Leegwater, Melissa Del Rios
core  

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Front-End Planning – The Role Of Project Governance And Its Impact On Scope Change Management

open access: yesInternational Journal of Technology, 2017
To achieve optimal value from investment in a project there must be a clear link between the outputs created by the project and the goals of the organization.
Eric Too, Tiendung Le, Wei Yee Yap
doaj   +1 more source

The Influence of Trust in Traditional Contracting: Investigating the "Lived Experience" of Stakeholders [PDF]

open access: yes, 2015
The traditional procurement approach is ever-present within the construction industry. With fundamental design principles founded on definitive risk allocation, this transactional based approach fails to acknowledge or foster the cooperative ...
Brewer, Graham   +2 more
core   +3 more sources

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

The Influence of Project Manager’s Age on Project Success [PDF]

open access: yesJournal of Engineering, Project, and Production Management, 2019
The world population is aging rapidly. The United Nations listed aging as one of the main social transformations of the twenty-first century. Aging impacts project managers as well.
Luli Hoxha, Cheryl McMahan
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Determinants of project success [PDF]

open access: yes
The interactions of numerous project characteristics, with particular reference to project performance, were studied. Determinants of success are identified along with the accompanying implications for client organization, parent organization, project ...
Baker, B. N., Fisher, D., Murphy, D. C.
core   +1 more source

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