Results 61 to 70 of about 3,592,985 (311)

Project management guide for student project teams [PDF]

open access: yes, 2011
Project based learning is a methodology based on students’ teams developing interdisciplinary work to deliver an outcome as a result of a project.
Almeida, Natália   +3 more
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Urbanist workshops between theory and practice: The importance of spatial and programme reference levels in the planning method [PDF]

open access: yesIgra Ustvarjalnosti, 2013
One of the key characteristics of urban-architectural workshops as a soft planning method is above all the fact that the authors are free of burden of formal facts and reference levels of the local environment, which do not influence the concept and the ...
Gregor Čok
doaj   +1 more source

Project Work in EAP: Methodological Considerations and Practical Applicability

open access: yesSelected papers on theoretical and applied linguistics, 1997
Selected papers on theoretical and applied linguistics, Vol 10 (1997): Proceedings of the 10th International Symposium on Theoretical and Applied Linguistics, Thessaloniki 24-26 April ...
openaire   +2 more sources

Sustainable Use of Natural Resources In Construction Works: a Case Study of Social Housing. [PDF]

open access: yes, 2017
Optimizing the use of resources in the building process is a current problem and is also highly regarded in the latest European legislation. The problem can be tackled by minimizing waste production, promoting waste recovery and transforming waste into ...
Paparella, Rossana
core  

A constitutive model for analyzing martensite formation in austenitic steels deforming at high strain rates [PDF]

open access: yes, 2006
This study presents a constitutive model for steels exhibiting SIMT, based on previous seminal works, and the corresponding methodology to estimate their parameters.
ZAERA, Ramon   +5 more
core   +5 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

The ECOSENSUS Project: Co-Evolving Tools, Practices and Open Content for Participatory Natural Resource Management [PDF]

open access: yes, 2006
ECOSENSUS (Electronic/Ecological Collaborative Sensemaking Support System)[www.ecosensus.info] is an ESRC e-Social Science pilot project, using a Participatory Action Research methodology to evolve tools and work practices for collaborative work in ...
Bachler, Michelle   +7 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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