Results 81 to 90 of about 3,619,509 (312)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Collaboration in the Archive

open access: yesExchanges
In this piece we look at a collaborative project, in which the Modern Records Centre is a co-lead: the Railway Work, Life & Death project. The project is transcribing details of accidents to British and Irish railway staff before 1939.
Mike Esbester   +4 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Use of project activity in integrated teaching of the English and Kazakh languages to students of economics faculty [PDF]

open access: yes
In the work we gave the definition of the project activity and considered the use of the project activity in the integrated teaching of the English and Kazakh languages to students of the faculty of economics.Project, integrated teaching, methodology ...
Moldakhmetova, Gulnara
core   +1 more source

Learning Community Group Concept Mapping: Fall 2014 Outreach and Recruitment, Spring 2015 Case Management and Service Delivery. Final Reports [PDF]

open access: yes, 2016
Beginning in 2014, the Federal Government provided funding to New York State as part of an initiative to improve services that lead to sustainable outcomes for youth receiving Supplemental Security Income (SSI) benefits.
Golden, Thomas P   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

ATHENE : Assistive technologies for healthy living in elders : needs assessment by ethnography [PDF]

open access: yes, 2011
Numerous assistive technologies to support independent living –including personal alarms, mobile phones, self-monitoring devices, mobility aids, software apps and home adaptations –have been developed over the years, but their uptake by older people ...
Dewsbury, Guy   +4 more
core   +1 more source

A constitutive model for analyzing martensite formation in austenitic steels deforming at high strain rates [PDF]

open access: yes, 2006
This study presents a constitutive model for steels exhibiting SIMT, based on previous seminal works, and the corresponding methodology to estimate their parameters.
ZAERA, Ramon   +5 more
core   +5 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

CacophonyViz: Visualisation of Birdsong Derived Ecological Health Indicators [PDF]

open access: yes, 2018
The purpose of this work was to create an easy to interpret visualisation of a simple index that represents the quantity and quality of bird life in New Zealand.
Hunt, Tim D., Nikora, Mark
core  

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