Results 161 to 170 of about 11,611,558 (295)
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
A new method of projection-based inference in GMM with weakly identified nuisance parameters [PDF]
Projection-based methods of inference on subsets of parameters are useful for obtaining tests that do not over-reject the true parameter values. However, they are also often criticized for being conservative.
Saraswata Chaudhuri, Eric Zivot
core
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Runge-Kutta-Chebyshev projection method
In this paper a fully explicit, stabilized projection method called the Runge–Kutta–Chebyshev (RKC) projection method is presented for the solution of incompressible Navier–Stokes systems.
Zheming Zheng, Linda Petzold
core
The project method originates from Pragmatism, the philosophical movement which appeared in the middle of the 19th century and promotes action and practical application of knowledge in everyday life. Major proponents of Pragmatism were J. Dewey (1935) and W. Kilpatrick (1935) in the USA and H. Gaudig in Germany.
openaire +1 more source
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
The Ends of Things Show Disc 01 [Projection]
The Theatre and Dance Platform holds a digital copy (MP4) of a video on Mini DV in the Lucy Guerin Inc collection.Projection for Lucy Guerin's The Ends of Things. Projection comprises eleven sections: 1. Colour Bars and Test Tone (0:52); 2.
Lucy Guerin Inc
core
Projection method for improving signal to noise ratio of localized surface plasmon resonance biosensors. [PDF]
Abumazwed A +4 more
europepmc +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source

