Results 141 to 150 of about 11,611,558 (295)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Reservoir of Giving I and II Show Disc 01 [Projection]

, 2005
The Theatre and Dance Platform holds a digital copy of the video file (MP4) stored on DVD (show disc) in the Lucy Guerin Inc collection.Projection for Lucy Guerin's "Reservoir of Giving I and II", part of the Love Me programme.
Rozetzky, David
core  

An alternative extragradient projection method for quasi-equilibrium problems. [PDF]

J Inequal Appl, 2018
Chen H, Wang Y, Xu Y.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Local Instrumental Variable Estimation Method for Generalized Additive Volatility Models [PDF]

We investigate a new separable nonparametric model for time series, which includes many ARCH models and AR models already discussed in the literature.
Woocheol Kim, Oliver Linton
core  

Gradient projection method with a new step size for the split feasibility problem. [PDF]

J Inequal Appl, 2018
Tianchai P.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A First Look on the New Halle Economic Projection Model [PDF]

In this paper we develop a small open economy model explaining the joint determination of output, inflation, interest rates, unemployment and the exchange rate in a multi-country framework.
Oliver Holtemöller, Rolf Scheufele, Sebastian Giesen, Juliane Scharff   +3 more
core  

Global convergence in a hybrid conjugate gradient projection method for finding solutions of constrained nonlinear equations with applications. [PDF]

PLoS One
Xia Y, Li D, Wang S.
europepmc   +1 more source