Results 61 to 70 of about 826 (213)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
A Patch/Dipole Hybrid-Mode Antenna for Sub-6GHz Communication
A low-profile antenna with a high gain and broad bandwidth is proposed for Sub-6GHz communication in this paper. A narrow-band patch mode and a narrow-band dipole mode are shared in one radiator and simultaneously excited to broaden the bandwidth.
Bei Huang +5 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
This letter reports inlet flow disturbance effects on direct numerical simulation of incompressible round jet at Reynolds number 2500. The simulation employs an accurate projection method in which a sixth order biased upwind difference scheme is used for
Zejing Hu, Yongliang Zhang, Zuojin Zhu
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
A Projection Analysis of News Critical Literacy Among Chinese EFL Learners: An SFL Approach
Critical literacy in EFL context has been examined from different perspectives. However, there is limited empirical evidence of how news critical literacy is examined discursively among college EFL learners.
Zaibing Luo, Pan Xie
doaj +1 more source
Character Segmentation and Recognition for Myanmar Warning Signboard Images
This paper publicizes the character segmentation and recognition of the Myanmar warning text signboard images taken by a mobile phone camera in natural scene. In this system, two templates are created.
Kyi Pyar Zaw, Zin Mar Kyu
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The Advancing Potential of Tutor Technologies in the Senior Students Training in the High School
The paper is devoted to the tutoring system in the modern high school. The system in question is based on the complex developmental educational technology of personalized teaching, aimed at identifying students’ educational motives and interests, and ...
Y. A. Lyakh
doaj +1 more source

