Results 61 to 70 of about 145,936 (263)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A Patch/Dipole Hybrid-Mode Antenna for Sub-6GHz Communication

open access: yesSensors, 2019
A low-profile antenna with a high gain and broad bandwidth is proposed for Sub-6GHz communication in this paper. A narrow-band patch mode and a narrow-band dipole mode are shared in one radiator and simultaneously excited to broaden the bandwidth.
Bei Huang   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A Projection Analysis of News Critical Literacy Among Chinese EFL Learners: An SFL Approach

open access: yesSAGE Open
Critical literacy in EFL context has been examined from different perspectives. However, there is limited empirical evidence of how news critical literacy is examined discursively among college EFL learners.
Zaibing Luo, Pan Xie
doaj   +1 more source

Inlet flow disturbance effects on direct numerical simulation of incompressible round jet at Reynolds number 2500

open access: yesTheoretical and Applied Mechanics Letters, 2018
This letter reports inlet flow disturbance effects on direct numerical simulation of incompressible round jet at Reynolds number 2500. The simulation employs an accurate projection method in which a sixth order biased upwind difference scheme is used for
Zejing Hu, Yongliang Zhang, Zuojin Zhu
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Character Segmentation and Recognition for Myanmar Warning Signboard Images

open access: yesInternational Journal of Networked and Distributed Computing (IJNDC), 2019
This paper publicizes the character segmentation and recognition of the Myanmar warning text signboard images taken by a mobile phone camera in natural scene. In this system, two templates are created.
Kyi Pyar Zaw, Zin Mar Kyu
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Advancing Potential of Tutor Technologies in the Senior Students Training in the High School

open access: yesОбразование и наука, 2015
The paper is devoted to the tutoring system in the modern high school. The system in question is based on the complex developmental educational technology of personalized teaching, aimed at identifying students’ educational motives and interests, and ...
Y. A. Lyakh
doaj   +1 more source

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