Results 91 to 100 of about 2,365 (306)
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Plane and projective meanders [PDF]
, 1993 This paper considers combinatorial properties of meanders — nonself-intersecting curves on the euclidean and projective plane. Both theoretical and numerical results are given, and various connections with other domains in mathematics are ...
Zvonkin, A.K., Lando, S.K.
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Real projective structures on a real curve [PDF]
, 2012 Given a compact connected Riemann surface X equipped with an antiholomorphic involution τ, we consider the projective structures on X satisfying a compatibility condition with respect to τ.
Biswas, Indranil, Hurtubise, Jacques
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Дифференциальная геометрия многообразий фигур, 2018 The article deals with hypercentered planes family in projective space. It is proved that the curvature object for the fundamental-group connection in the principal bundle associated with the family is a tensor.
K. Bashashina
doaj
Differentiable Manifolds and Geometric Structures
MathematicsThis editorial presents 26 research articles published in the Special Issue entitled Differentiable Manifolds and Geometric Structures of the MDPI Mathematics journal, which covers a wide range of topics particularly from the geometry of (pseudo ...
Adara M. Blaga
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
The Lamé family of connections on the projective line [PDF]
, 2008 International audienceThis paper deals with rank two connections on the projective line having four simple poles with prescribed local exponents 1/4 and -1/4. This Lamé family of connections has been extensively studied in the literature.
Loray, Frank +2 more
core
Affine and projective transformations of Berwald connections [PDF]
, 2007 We discuss the infinitesimal affine transformations of the Berwald connection of a spray, and the relation between the projective transformations of a spray and the affine transformations of its Berwald–Thomas–Whitehead ...
Saunders, D.J. +4 more
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