Results 101 to 110 of about 7,890,386 (291)

Quantum Dimension and Quantum Projective Spaces [PDF]

Symmetry, Integrability and Geometry: Methods and Applications, 2014
We show that the family of spectral triples for quantum projective spaces introduced by D'Andrea and Dabrowski, which have spectral dimension equal to zero, can be reconsidered as modular spectral triples by taking into account the action of the element $K_{2 }$ or its inverse. The spectral dimension computed in this sense coincides with the dimension
openaire   +4 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Algebraic invariants of edge ideals from strong products of paths and cycles

AIMS Mathematics
This paper investigates algebraic invariants of edge ideals associated with families of graphs constructed as the strong product of a path or cycle with the complete graph $ K_m $, namely $ \mathscr{P}_\gamma = P_\gamma \boxtimes K_m $ and $ \mathscr{C}_\
Ahtsham Ul Haq, Muhammad Usman Rashid, Muhammad Ishaq   +2 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

The Numerical Class of a Surface on a Toric Manifold

International Journal of Mathematics and Mathematical Sciences, 2012
In this paper, we give a method to describe the numerical class of a torus invariant surface on a projective toric manifold. As applications, we can classify toric 2-Fano manifolds of the Picard number 2 or of dimension at most 4.
Hiroshi Sato
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

On the moduli space of superminimal surfaces in spheres

International Journal of Mathematics and Mathematical Sciences, 2003
Using a birational correspondence between the twistor space of S2n and projective space, we describe, up to birational equivalence, the moduli space of superminimal surfaces in S2n of degree d as curves of degree d in projective space satisfying a ...
Luis Fernández
doaj   +1 more source

Projective cyclic groups in higher dimensions

Linear Algebra and its Applications, 2017
In this article we provide a classification of the projective transformations in $PSL(n+1,\Bbb{C})$ considered as automorphisms of the complex projective space $\Bbb{P}^n$. Our classification is an interplay between algebra and dynamics, which just as in the case of isometries of CAT(0)-spaces, can be given by means of tree three types, namely ...
Angel Cano, Luis Loeza, Alejandro Ucan-Puc   +2 more
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source