Results 81 to 90 of about 134,827 (278)
The Numerical Class of a Surface on a Toric Manifold
International Journal of Mathematics and Mathematical Sciences, 2012 In this paper, we give a method to describe the numerical class of a torus invariant surface on a projective toric manifold. As applications, we can classify toric 2-Fano manifolds of the Picard number 2 or of dimension at most 4.
Hiroshi Sato
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
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Finite Flat and Projective Dimension
Communications in Algebra, 2005 Over a right-noetherian algebra admitting a dualizing complex, any left-module with finite flat dimension also has finite projective dimension.
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
On the moduli space of superminimal surfaces in spheres
International Journal of Mathematics and Mathematical Sciences, 2003 Using a birational correspondence between the twistor space of S2n and projective space, we describe, up to birational equivalence, the moduli space of superminimal surfaces in S2n of degree d as curves of degree d in projective space satisfying a ...
Luis Fernández
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
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On fitting ideals of second order universal modules of derivatives
Mathematics OpenLet k be an algebraically closed field with characteristic zero, [Formula: see text] and S be polynomial algebras over k. In [15], it has been shown the first nonzero Fitting ideals of [Formula: see text] and [Formula: see text] are invertible, then so ...
Nurbige Turan Zabun, Necati Olgun
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On modules of finite projective dimension [PDF]
Nagoya Mathematical Journal, 2015 Abstract We address two aspects of finitely generated modules of finite projective dimension over local rings and their connection in between: embeddability and grade of order ideals of minimal generators of syzygies. We provide a solution of the embeddability problem and prove important reductions and special cases of the order ideal conjecture. In
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
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