Results 61 to 70 of about 134,827 (278)

2-elements in an Autotopism Group of a Semifield Projective Plane

Известия Иркутского государственного университета: Серия "Математика", 2022
We investigate the well-known hypothesis of D.R. Hughes that the full collineation group of non-Desarguesian semifield projective plane of a finite order is solvable (the question 11.76 in Kourovka notebook was written down by N.D. Podufalov). The spread
Olga Kravtsova
doaj   +1 more source

Contour projected dimension reduction

The Annals of Statistics, 2009
Published in at http://dx.doi.org/10.1214/08-AOS679 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Luo, Ronghua, Wang, Hansheng, Tsai, Chih-Ling   +2 more
openaire   +4 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cohomological and projective dimensions [PDF]

Compositio Mathematica, 2013
AbstractLet $\mathfrak{a}$ be a homogeneous ideal of a polynomial ring $R$ in $n$ variables over a field $\mathbb{k}$. Assume that $\mathrm{depth} (R/ \mathfrak{a})\geq t$, where $t$ is some number in $\{ 0, \ldots , n\} $. A result of Peskine and Szpiro says that if $\mathrm{char} (\mathbb{k})\gt 0$, then the local cohomology modules ${ H}_{\mathfrak ...
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Topological Complexity and LS-Category of Certain Manifolds

Journal of Mathematics, 2023
The Lusternik–Schnirelmann category and topological complexity are important invariants of topological spaces. In this paper, we calculate the Lusternik–Schnirelmann category and topological complexity of products of real projective spaces and their ...
Fezzeh Akhtarifar, Mohammad A. Asadi-Golmankhaneh   +1 more
doaj   +1 more source

Projection theorems using effective dimension

Information and Computation
In this paper we use the theory of computing to study fractal dimensions of projections in Euclidean spaces. A fundamental result in fractal geometry is Marstrand's projection theorem, which shows that for every analytic set E, for almost every line L, the Hausdorff dimension of the orthogonal projection of E onto L is maximal.
Lutz, Neil, Stull, Donald M.
openaire   +6 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source