Results 71 to 80 of about 134,827 (278)

Multivariate response directional regression: a projective resampling approach

Journal of Big Data
In high dimensional data analysis, directional regression is a widely used method for implementing linear sufficient dimension reduction by extracting core information from the complex data structure.
Ahreum Lee, Kyongwon Kim
doaj   +1 more source

Modified Function Projective Synchronization between Different Dimension Fractional-Order Chaotic Systems

Abstract and Applied Analysis, 2012
A modified function projective synchronization (MFPS) scheme for different dimension fractional-order chaotic systems is presented via fractional order derivative.
Ping Zhou, Rui Ding
doaj   +1 more source

Simple modules over Auslander regular rings

Open Mathematics, 2017
In this paper, we discuss the properties of simple modules over Auslander regular rings with global dimension at most 3. Using grade theory, we show the right projective dimension of ExtΛ1(S,Λ)$\begin{array}{} \text{Ext}_{{\it\Lambda}}^{1}(S,\ {\it ...
Huang Chonghui, Zheng Lijing
doaj   +1 more source

Stability of Gorenstein objects in triangulated categories [PDF]

, 2014
Let $\mathcal{C}$ be a triangulated category with a proper class $\xi$ of triangles. Asadollahi and Salarian introduced and studied $\xi$-Gorenstein projective and $\xi$-Gorenstein injective objects, and developed Gorenstein homological algebra in ...
Liang, Chunli, Wang, Zhanping
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Left global dimensions and inverse polynomial modules

International Journal of Mathematics and Mathematical Sciences, 2000
We prove the fact l.gl.dimR[x]=(l.gl.dimR)+1, where l.gl.dim means the left global dimension by using inverse polynomial modules and injective dimensions.
Sangwon Park
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Groups of permutation projective dimension two [PDF]

Proceedings of the American Mathematical Society, 1984
In previous papers we developed a version of homological algebra for Z [ G ] Z[G] modules ( G G a finite group) using summands of permutation modules in place of projective modules. The resulting theory is more discriminating than the usual homological algebra. For example, an f.g.
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source