Results 171 to 180 of about 1,035 (266)

New biosensors and transgenic mice for multiplex cGMP imaging

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters   +6 more
wiley   +1 more source

Some remarks about deformation theory and formality conjecture. [PDF]

open access: yesAnn Univ Ferrara Sez 7 Sci Mat
Chen H, Pertusi L, Zhao X.
europepmc   +1 more source

Modelling Hierarchical Configurations in Innovation Research With Two‐Step QCA: Methodological Recommendations and an Application to Workarounds

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT Creativity and innovation are often understood as the result of a complex interplay of hierarchical factors, such as national, regional and firm characteristics, or between organisational and individual factors. While recent applications of qualitative comparative analysis (QCA) have begun to model such configurational links, their ...
Luc Sandfort   +3 more
wiley   +1 more source

Characterizing barren plateaus in quantum ansätze with the adjoint representation. [PDF]

open access: yesNat Commun
Fontana E   +7 more
europepmc   +1 more source

Affinification: A Fine Approximation of Deformations

open access: yesComputer Graphics Forum, EarlyView.
Abstract We introduce affinification, a novel method for accelerating physics‐based animation of elastic solids. During a time‐dependent simulation, our method automatically partitions the space into affine and elastic regions depending on the deformation.
A. Mercier‐Aubin   +3 more
wiley   +1 more source

Projective hypersurfaces in tropical scheme theory I: the Macaulay ideal. [PDF]

open access: yesRes Math Sci
Fink A   +3 more
europepmc   +1 more source

Progressively Projected Newton's Method

open access: yesComputer Graphics Forum, EarlyView.
Abstract Newton's Method is widely used to find the solution of complex non‐linear simulation problems. To guarantee a descent direction, it is common practice to clamp the negative eigenvalues of each element Hessian prior to assembly—a strategy known as Projected Newton (PN)—but this perturbation often hinders convergence.
J. A. Fernández‐Fernández   +2 more
wiley   +1 more source

Hierarchical Optimization of the As‐Rigid‐As‐Possible Energy

open access: yesComputer Graphics Forum, EarlyView.
Abstract The As‐Rigid‐As‐Possible (ARAP) energy [SA07] has become a versatile ingredient in various geometry processing and machine learning methods. The classic method for its minimization is a block coordinate descent, alternating between local rotation estimation and a global linear solve, which converges slowly for large problem instances.
Hendrik Meyer, Bernd Bickel, Marc Alexa
wiley   +1 more source

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