Results 101 to 110 of about 188,835 (324)

Special Kähler geometry and holomorphic Lagrangian fibrations

open access: yesComptes Rendus. Mathématique
Given a holomorphic Lagrangian fibration of a compact hyperkähler manifold, we use the differential geometry of the special Kähler metric that exists on the base away from the discriminant locus, and show that the pullback of the tangent bundle of the ...
Li, Yang, Tosatti, Valentino
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Integrating the Projective Transform with Particle Filtering for Visual Tracking

open access: yesEURASIP Journal on Image and Video Processing, 2011
This paper presents the projective particle filter, a Bayesian filtering technique integrating the projective transform, which describes the distortion of vehicle trajectories on the camera plane.
Beghdadi A   +3 more
doaj  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Projective crystal symmetry and topological phases

open access: yesMaterials Today Quantum
Quantum states naturally represent symmetry groups, though often in a projective sense. Intriguingly, the projective nature of crystalline symmetries has remained underexplored until very recently.
Chen Zhang, Shengyuan A. Yang, Y.X. Zhao
doaj   +1 more source

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