Results 141 to 150 of about 103,657 (309)

Application of Sizing Estimation Techniques for Business Critical Software Project Management [PDF]

, 2014
Parvez Mahmood Khan, M. M. Sufyan Beg
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Enhancing the record through remote sensing: the application and integration of multi-sensor, non-invasive remote sensing techniques for the enhancement of the Sites and Monuments Record. Heslerton Parish Project, N. Yorkshire, England

, 1997
Dominic Powlesland, James Lyall, Daniel N.M. Donoghue   +2 more
openalex   +2 more sources

Project 8: Using Radio-Frequency Techniques to Measure Neutrino Mass [PDF]

, 2013
N. S. Oblath
openalex   +1 more source

Estimation Techniques for Sample Project – Acoustical Ceilings, Drywall, Structural Concrete, and Rebar with Sample Proposal

, 2021
M. A. Grubb
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Technique for Assessment of Ecological and Economical Efficiency of Projects in the Road Construction Area [PDF]

, 2015
Артеменков, Andrey Igorevich Artemenkov, Медведева, Olga Medvedeva, Трофименко, Yuri Trofimenko, Медведев, Pavel Medvedev   +7 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Morphometric Analysis of Mandibular Ramus Indices for Sex Prediction Using Digital Orthopantomograms (OPGs) and the GNU Image Manipulation Program (GIMP) Software. [PDF]

Cureus
Thube HR, Vaswani V, Chandwani N, Shrigiriwar M.   +3 more
europepmc   +1 more source