Results 61 to 70 of about 99,376 (279)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Projective techniques: Are they a victim of clashing paradigms? [PDF]
This paper reviews the concept and historical development of projective techniques. It considers why, given the importance of their psychoanalytical foundations to the underlying paradigms of management theory, they have been generally marginalised as a ...
Boddy, Clive R. +2 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A projective approach to a language of landscape design
Landscape Review, 1997 Building on the work of Kelly (1955) in personal construct psychology, and Peled (1976, I990) in ecoanalysis, this paper develops projective techniques-which use concepts of personal and phenomenological space-as a means for articulating approaches to ...
Catherine Ward Thompson
doaj
Jornal Brasileiro de Psiquiatria, 2008 OBJECTIVE: The study presents the Brazilian norms for 240 new stimuli from International Affective Picture System (IAPS), a database of affective images widely used in research, compared to the North-American normative ratings.
Cristina Lasaitis +2 more
doaj +1 more source
Disruptions from a Traumatic Event: A Clinical Vignette [PDF]
, 2012 The paper presents a clinical vignette regarding the psychological assessment of a seven years old boy, following a traumatic event, an accident with a bus that resulted in his grandfather’s death.
Campos, Rui C.
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Techniques for approaching the dual Ramsey property in the projective hierarchy [PDF]
, 2001 We define the dualizations of objects and concepts which are essential for investigating the Ramsey property in the first levels of the projective hierarchy, prove a forcing equivalence theorem for dual Mathias forcing and dual Laver forcing, and show ...
Halbeisen, Lorenz, Loewe, Benedikt
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Optimal Ferrers Diagram Rank-Metric Codes [PDF]
, 2014 Optimal rank-metric codes in Ferrers diagrams are considered. Such codes consist of matrices having zeros at certain fixed positions and can be used to construct good codes in the projective space.
Etzion, Tuvi, Wachter-Zeh, Antonia
core